COMPARISION OF DEXMEDETOMIDINE AND CLONIDINE WITH ROPIVACAINE BY EPIDURAL ROUTE IN PATIENTS UNDERGOING LOWER ABDOMINAL SURGERIES
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 12
Abstract
BACKGROUND Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage or as described in terms of such damage. Regional anesthetic procedure is a need for local anesthetic with desirable properties like longer duration of sensory blockade and lesser duration of motor paralysis. We wanted to evaluate the efficacy of Inj. Dexmedetomidine (1.5 µg/kg) with 0.75% Ropivacaine by epidural route compared to Inj. Clonidine (2 µg/kg) with 0.75% Ropivacaine by epidural route in patients undergoing lower abdominal surgeries. MATERIALS AND METHODS In this study, 50 patients belonging to ASA grade I and II undergoing elective lower abdominal surgeries were randomly divided into two groups by lottery method. Group RC (Control): The control group comprises of patients in whom 19 ml of 0.75% Ropivacaine with Inj. clonidine 2 µg/Kg (made to 1 ml) administered epidurally. Group RD (Study group): Consists of patients in whom 19 ml of 0.75% Ropivacaine with inj. Dexmedetomidine – 1.5 μg/Kg (made to 1 ml) was administered epidurally. RESULTS The mean time of onset of sensory blockade, 2 segment regression time in Dexmedetomidine group is significantly less than Clonidine group. The mean duration of sensory blockade was significantly higher with Dexmedetomidine group than Clonidine group. The mean time of onset and duration of motor blockade was significantly less in Dexmedetomidine group than Clonidine group and control group. The duration of analgesia was significantly prolonged and highest in the Dexmedetomidine group compared to Clonidine group. CONCLUSION We conclude that dexmedetomidine is a better adjuvant than clonidine in epidural anesthesia as far as patient comfort, stable cardio-respiratory parameters, intra-operative and post-operative analgesia are concerned.
Authors and Affiliations
Sai Naveena Lakshmi Bitra, Thanuja Rajya Lakshmi Devi Peddada
Keywords
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- EP ID EP615671
- DOI 10.18410/jebmh/2019/210
- Views 84
- Downloads 0
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