Comparision of Etomidate versus Propofol for Anaesthesia in Short Case Surgical Procedures
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 4
Abstract
Background: Etomidate and Propofolare two ultra short-acting IV induction agents. Studies for long duration surgeries found that etomidate provides ef ective, reliable anaesthesia, rapid recovery and minimal side ef ect but very less studies are available for short duration surgical procedures. A present study was aimed to evaluate hemodynamicchanges, compare duration of recovery from anaesthesia and compare safety of both drugs. Material and Methods: We conducted single centred, open labelled, parallel group Randomised Control Trial on 60 patients between 18 to 60 years age, having physical status ASA I, II or III undergoing elective or emergency short (less than or equal to 30 minutes) surgical procedures. Patients who met inclusion criteria were randomly divided into two groups of 30 each based on computer generated software after taking written and informed consent. Patients were given premedication and IV induction agent (loading dose) followed by i.v. infusion according to their group. Results: Mean of Modified Aldrete Score and Modified Observer's Assessment of Alertness Score were 9.06 & 9.87, 4.25 &4.9; Group P and E respectively. Mean variation of HR and MAP after 5 mins of induction was less significant. But SPO2 was 2.57 and 0.17, in group P & E respectively (P value=0.026). Recovery duration from anaesthesia was much rapid and faster in Group E. Fewer side effects were observed in group E. Conclusions: Etomidate was haemo dynamically more stable and showed rapid recovery and lesser sideeffects in comparision to propofol. But both were equally efficacious
Authors and Affiliations
Dr Karan M Patel
Keywords
Related Articles
- EP ID EP284916
- DOI -
- Views 101
- Downloads 0
Para Spinal Mass with Multiple Differential Diagnosis- A Case report
A paraspinal mass may be caused by large number of conditions including an abscess, non specific lesions and benign & malignant conditions involving mesenchymal/soft tissues. The diagnosis of many such lesions may be don...
A Study of Urea, Uric Acid and Creatinine Pathogenesis of Oral Submucous Fibrosis
Oral Submucous Fibrosis (OSMF) is a high risk precancerous condition, chronic debilitating disease of the oral cavity characterized by inflammation and preogressive fibrosis of the submucosal tissues (Lamina Propariaand...
Study of pulmonary infection in patients with diabetes Mellitus
Patients with diabetes mellitus are at higher risk of developing pulmonary infections; this study was conducted to study Pulmonary infection in patients with Diabetes mellitus. Material and Method: 50 known cases of Diab...
Early Markers for the Prediction of Hyperbilirubinemia in Term Neonates
Abstract
Evaluation of the adverse drug reaction information for the multidrug resistant tuberculosis (MDR-TB) patients in a TB hospital in Mumbai (India)
Introduction: Second line drug treatment regimens for Drug Resistant Tuberculosis (DRTB) are lengthy and toxic, presenting a challenge to patient compliance. Information Education Communication (ICE) material usually lac...