Comparision of Prevalance of Candida Species in Healthy Individuals, Patients with Habits, Oral Leukoplakia and Oral Cancer
Journal Title: Scholars Journal of Dental Sciences - Year 2018, Vol 5, Issue 12
Abstract
Candida species constitute part of the oral harmless commensal flora in about 2–70% of the general population but disequilibrium in the homeostasis between Candida, host immune system and normal oral bacterial flora favors Candida virulence which causes damage to the tissues which may increase the risk of a premalignant and malignant lesion. The aim of this study is to evaluate the prevalence of Candida infections in patients with history of habits, Oral leukoplakia and history of Oral Squamous cell carcinoma in comparision to healthy indiviuals. The present study included 20 patients with habits, 20 patients with premalignant lesions, 20 patients with known case of cancer and 20 healthy controls. A detailed history of each patient was recorded along with a clinical examination. Samples were collected with the swab and oral rinse technique, cultured on Sabouraud’s agar medium. The isolated yeast species were identified based on Gram staining, a Germ tube test, Hichrome Candidal differential agar for speciation. Of the 80 samples collected Candida was isolated in 30 specimens. Out of 30 positive Candida species 21 was Candida albicans 06 was Candida glabrata and 03 were Candida tropicalis. Candida species were most isolated in Group IV ie Oral Carcinoma 11 (36.6%) followed by group III ie Oral leukoplakia. The incidence of Candida (primarily C. albicans) was maximum in Oral Carcinoma 11 (36.6%) followed by Oral leukoplakia. The findings of the present study suggest that elevated Candidal carriage were seen in patients with potentially malignant disorders and OSCC. Hence there must be a possible association between the developments of oral squamous cell carcinoma in potentially malignant oral lesions with chronic candidal infection due to Candida-associated malignant transformation”
Authors and Affiliations
Dr. Rafath Fatima, Dr. Shereen Fatima
Keywords
Related Articles
- EP ID EP488583
- DOI -
- Views 65
- Downloads 0
Study of Distance Measurement of the Alveolar Crest to Maxillary Sinus Floor on Different Views of CBCT
Abstract: Knowledge of the exact location of the floor of maxillary sinus is a very important factor in relation to safe regions for implant therapy and surgery. The aim of this study was to evaluate the distance between...
Treatment of Multiple Complicated Crown–Root Fracture of Maxiller Central Incisors: case report
Abstract: This case report describes the surgical, endodontic, and restorative treatment for the management of two complicated crown root fractures of maxillary central incisors. A 25-year-old male patient was referred...
Gingival Tissue Status and the Patients’ Satisfaction on Anterior Labial Gingival Color Among Yemeni Patients in Abha City of Saudi Arabia
Gingival pigmentation is a change of gingival color due to different factors, lesions and conditions. Clinical discoloration of gingival is considered as medical problem (disease or patient esthetic concern) ; although t...
Single-rooted primary molar in a little girl with Ectodermal dysplasia: A rare case
The aim of this study was to present a rare case of a single-rooted primary molar that is associated with syndromichypodontia. Dental anomalies, especially permanent single-rooted molars are fairly common between the sec...
Restricted Mouth Opening - Impressions making
Abstract: Prosthodontics starts with a good impression and a good impression always leads to a good prosthesis. An adequate mouth opening is mandatory for a good impression making. Restricted mouth opening is a relative...