Comparism of Antioxidants Status among Children, Teenagers and Adults with Sickle Cell Anaemia.
Journal Title: International Journal of Engineering and Science Invention - Year 2017, Vol 6, Issue 7
Abstract
Background: One of the diseases caused by a mutation in a gene is sickle cell anaemia. Sickle cell anaemia is a serious disorder in which the body makes sickle-shaped red blood cells. The sickle cells block blood flow in the blood vessels, this causes pain as well as organ damage, and it can also raise the risk of infection. Materials and methods: This study was carried out to determine, as well as compare, the activities of enzymatic antioxidants- Glutathione peroxidase (GPx), Catalase (Cat) and Superoxide dismutase (SOD), as well as some non- enzymatic antioxidants (Vitamins C and E ), in the plasma of sickle cell , non-sickle cell and sickle cell trait children, teenagers and adults. Sixty adults were grouped into 3 groups of 20 subjects each; the groups were having the status of AA, AS, and SS respectively. The same grouping arrangement was made for 60 teenagers and 60 children respectively. The subjects for the study were gotten from Federal medical center, Ido Ekiti and some selected hospitals in Ekiti state. All the antioxidants were determined using standard laboratory methods respectively. Results: The results obtained showed significant reductions (P<0.05) in the concentrations of all the antioxidants in the sickle cell subjects, at all ages - children, teenagers and adults. Conclusion: This study suggests that both enzymatic and non-enzymatic antioxidants are implicated in sickle cell anaemia irrespective of the stage and age of the carrier.
Authors and Affiliations
Oyeyemi A. O, Sonuga A. A, Oyebanji O. G
Keywords
Related Articles
- EP ID EP403247
- DOI -
- Views 78
- Downloads 0
Switching Angle Calculation By EP, HEP, HH And FF Methods For Modified 11-Level Cascade H-Bridge Multilevel Inverter
In this paper the switching angles, from that the time required, to generate triggering pulses for IGBT switches of a single-phase Modified 11-Level Cascade H-Bridge Multilevel inverter is described by using Equal Phase...
Symmetry in Formation of Molecules
Different set of formulas for integer heron triangles are obtained.
Synthesis and Biological Evaluation of New Schiff Base Transition Metal Complexes
Schiff Base Complexes Derived From Dfmpm And Glutamic Acid With Co(Ii), Ni(Ii) And Cu(Ii) Were Synthesized And Characterized By Ir, Uv-Vis, Elemental Analysis, Molar Conductance, Powder Xrd And Sem. The Antimicrobial Act...
Radon in the Nature
Unique Radon-222 is a normally happening radioactive gas that is a piece of the Uranium rot arrangement. Its Presence in the earth is related predominantly with follow measures of uranium and its prompt parent, radium-22...
Global Political Mechanism G20-G8-G77 With Global Leadership, Intelligence Agency Theory And Conflicts Sexual Health,Capitalism Emperors ,Nation Guinea Kankanwest Africa.Compare, China And Russia United Nation, Security Council ,Law
The Study examines Global Influence,Guinea was proclaimed Independence on 2 October 1958, The territory voted to reject France’s offer of membership. (the Guinea superpower on 2029)However Global Guinea’s political leade...