Comparison between Corneal Collagen Cross-Linking with Epithelial Removal and Transepithelial for Management of Progressive Keratoconus
Journal Title: INTERNATIONAL INVENTION JOURNAL OF MEDICINE AND MEDICAL SCIENCES (IIJMMS) - Year 2016, Vol 3, Issue 3
Abstract
This study aim to compare the efficacy and safety of corneal cross linking (CXL) with and without removal of epithelium for treatment of progressive keratoconus. One eye of 16 patients with bilateral progressive keratoconus was randomly treated by corneal cross linking (CXL) with epithelium removal (group I) while the fellow eye underwent corneal cross linking (CXL) without epithelium removal (Transepithelial CXL group II). Visual acuity, refraction, corneal topography was evaluated at after 3, 6, and 12 months. In both groups uncorrected and corrected distance visual acuity improved significantly after treatment. There was a significant improvement in topographic outcomes, spherical equivalent and astigmatism in both groups at one year postoperatively. Postoperative pain was significantly less and shorter in duration in group II. The most significant difference between epithelium removal CXL and intact epithelium CXL (Transepithelial CXL) was short recovery as regard pain and epithelium healing. Both techniques were equally safe and effective in stabilization of keratoconus.
Authors and Affiliations
Mohamed El moddather
Keywords
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