Comparison between Outcome of Assisted Reproductive Technique (Art) Cycles with and Without OCP Pretreatment in Infertile Women: A Randomized Clinical Trial

Journal Title: Women's Health Science Journal - Year 2021, Vol 5, Issue 1

Abstract

The objective of this randomized clinical trial was to assess the effect of pretreatment with oral contraceptive pill (OCP) on assisted reproductive technique outcomes in patient’s candidate for assisted reproductive technique (ART). In a randomized clinical trial University-based infertility center, Tehran, Iran. 160 infertile patient who are candidate for IVF, randomly divided into two groups: 80 patients in OCP pretreatment group and 80 patients in non-OCP pretreatment group. The IVF protocol in all patients was standard long GnRH agonist (long protocol). The oocyte number, embryo formation, fertility rate, gonadotropin dose, ovarian cyst formation and cancelled cycles were evaluated. Oocytes number per patient in OCP group was 13.87 and in non-OCP group was 15.22, pregnancy rate in OCP group was 44.7% and in non-OCP was 31.2%, the abortion rate in OCP group was 10.5% and in non-OCP was 3.1%, that there was no significant difference between two groups, embryo formation in two groups was similar. ovarian cyst in OCP group was 2.6% and in non-OCP was 12.5% (P< 0.05) so the cancelled cycles due to ovarian cyst in OCP group was less than non-OCP group. Based on our data, OCP pretreatment have no effect on oocyte number, embryo formation, pregnancy rate and abortion, but this pretreatment can decrease the cyst formation so decrease the cancelled cycles in OCP pretreatment.

Authors and Affiliations

Heidar Z, Mirzamoradi M, Lapavandani RS*, Afshari A and Mirzaee S

Keywords

Related Articles

Knowledge, Practice and Acceptability of Cervical Cancer Screening among Midwives in the Gambia

Cervical cancer is one of the commonest malignancy among women in the world with an estimated 527,624 new cases and 265,653 deaths in 2012.The burden of cervical cancer in developing countries is huge with an incidence r...

Effect of the Islamic Based on Parenting Class Parents Parenting in Padangpanjang

The position of the family as the smallest unit of society has a role and responsibility first and foremost to maintain the growth and development of children. As parents not only meet the needs of the child outwardly bu...

Cornual Ectopic Pregnancy: Diagnostic and Therapeutic Difficulties, a Case Report at the Teaching Hospital of Angre / Abidjan (Ivory Coast)

Cornual ectopic pregnancy (CEP) is defined by implantation of the ovular sac in the rudimentary horn of a bicorn uterus. By extension, pregnancies implanted in the horn of a partitioned uterus or in the stump of a fallop...

Factors Associated with Home Deliveries in Katondwe, Luangwa District

Despite the policy to stopping traditional birth attendants from conducting deliveries at home and encouraging all women to give birth at the health facility under skilled care, many women still give birth at home. A qua...

Profile and Prognosis of Retro Placental Hematoma Victims at the Regional University Associated Hospital of Borgou (CUAB) in Republic of Benin

Objectives: Describe the prognosis and profile of the retro placental hematoma(RPH) at CUAB for a better organization of care. Methods: This is a descriptive retrospective study, carried out in the obstetric gynecology s...

Download PDF file
  • EP ID EP746498
  • DOI 10.23880/whsj-16000158
  • Views 44
  • Downloads 0

How To Cite

Heidar Z, Mirzamoradi M, Lapavandani RS*, Afshari A and Mirzaee S (2021). Comparison between Outcome of Assisted Reproductive Technique (Art) Cycles with and Without OCP Pretreatment in Infertile Women: A Randomized Clinical Trial. Women's Health Science Journal, 5(1), -. https://europub.co.uk/articles/-A-746498