COMPARISON BETWEEN TAB. CLONIDINE AND TAB. LABETALOL AS ORAL PREMEDICATION IN ATTENUATION OF HAEMODYNAMIC CHANGES DURING LAPAROSCOPIC SURGERY: A RANDOMISED DOUBLE BLIND STUDY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2016, Vol 3, Issue 16
Abstract
BACKGROUND AND AIMS To study and compare Labetalol and Clonidine as premedication to attenuate haemodynamic changes to Laparoscopy through oral route, as it is safe method of administration and easy to prescribe. METHODS In a prospective, comparative randomised study, 60 adult patients of both sexes of ASA Grade I and II were divided randomly into 2 groups of 30 each, Group L and Group C. Group L were given Tab. Labetalol 200mg orally 60-90 minutes before induction. Group C were given Tab. Clonidine 300µg orally 60-90 minutes before induction. We compared the degree of attenuation of haemodynamic changes during laparoscopic surgeries. RESULTS Oral Clonidine has better control on the rise in heart rate and mean arterial pressure (MAP) during laryngoscopy for laparoscopy compared to oral Labetalol. CONCLUSION We conclude that oral Clonidine showed better attenuation of haemodynamic changes than oral Labetalol.
Authors and Affiliations
Saroj Patta, Pradeep Kumar Karem, Krishna Chaitanya Bevara, Satyanarayana A
Keywords
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- EP ID EP233385
- DOI 10.18410/jebmh/2016/139
- Views 80
- Downloads 0
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