Comparison of 0.1% Tacrolimus & 0.1% Triamcinolone acetonide in Oral Lichen Planus - A Clinical Study
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2018, Vol 6, Issue 4
Abstract
Background: Lichen planus (LP) is a chronic mucocutaneous disorder that affects oral and genital mucous membranes, skin, nails, and scalp. The present study was conducted to compare 0.1%, triamcinolone acetonide and 0.1% tacrolimus in the management of oral lichen planus. Materials & Methods: The present study comprised of 50 patients of oral lichen planus which was confirmed by clinical examination followed by histopathological examination. They were divided into 2 groups of 25 each. Group I were those who were prescribed 0.1% tacrolimus 4 times daily and group II were put on 0.1% triamcinolone acetonide 4 times daily. Patients were recalled regularly to see improvement in the lesion and were recorded as improved and non- improved. Results: Pain was present in 12 patients in group I and 14 in group II and burning sensation was present in 17 in group I and 19 in group II patients. The difference was non- significant (P> 0.05). Improvement was seen in 18 in group I and 19 in group II and non improvement in 7 in group I and 6 in group II. The difference was non- significant (P> 0.05). Conclusion: OLP is an inflammatory mucosal and cutaneous disorder commonly seen among females. Both 0.1%, triamcinolone acetonide and 0.1% tacrolimus found to be effective in the management of oral lichen planus.
Authors and Affiliations
Adil Rasool Malik, Awadhesh Gupta
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