Comparison of 0.75%Isobaric Ropivacaine Alone And 0.75%Isobaric Ropivacaine with Fentanyl as Adjuvant in Spinal Anesthesia for Orthopaedic Lower Limb Surgeries
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 6
Abstract
Background: Fentanyl, a potent, short acting, synthetic opioid analgesic has been commonly used as an adjuvant with local anesthetics for post operative analgesia because of its superior intraoperative conditions, hemodynamic stability and minimal side-effects. The aim of this study was to evaluate the efficacy and safety of addition of Intrathecal Fentanyl to 0.75% Isobaric Ropivacaine in spinal anesthesia in orthopaedic lower limb surgeries. Subjects and Methods: Hundred patients belonging to American Society of Anesthesiologists physical status I and II scheduled for orthopedic lower limb surgery under spinal anesthesia were included. The study was a prospective double blinded randomized controlled trial where patients were randomly allocated into two groups of fifty patients each to receive either 2.6 ml of 0.75% (19.5 mg) isobaric ropivacaine with 0.4ml (20 μg) fentanyl (Group B) or 2.6 ml of 0.75% (19.5 mg) isobaric ropivacaine with 0.4 ml of 0.9% saline (Group A) intrathecally. The points studied were hemodynamic parameters, onset of sensory and motor blockade, duration of sensory and motor blockade, duration of analgesia, degree of sedation and side-effects were also assessed. At the end of study, data were systematically compiled and analyzed for statistical significance. Results: No significant difference was found in hemodynamics, onset of sensory block and incidence of side effects with the addition of fentanyl to ropivacaine. The intrathecal fentanyl has accelerated the onset time to achieve motor blockade. There was a significant prolongation of the duration of sensory block and postoperative analgesia in Group B. Conclusion: Intrathecal 20μg fentanyl is associated with prolonged sensory block, provides excellent quality of intraoperative and postoperative analgesia allowing early and pain free ambulation as compared to plain ropivacaine. It is haemodynamically stable in intraoperative and postoperative periods with insignificant side effects.
Authors and Affiliations
Mudita Bhatia
Keywords
Related Articles
- EP ID EP522397
- DOI -
- Views 76
- Downloads 0
64- Slice Multiple –Row Detector CT Angiography (MDCTA): Application in Peripheral Vascular Diseases
Background: With the improvements in design and techniques of advanced computed tomography techniques like multiple- row detector CT (MDCT), CT angiography of peripheral vasculature have become an easy, fast and feasible...
Avulsion Fracture of Anterior Superior Iliac Spine with Meralgia Paraesthetica: A Case Report
Avulsion fracture of the anterior superior iliac spine is a rare entity which may or may not be associated with meralgia paraesthetica. It is commonly seen in the adolescent age group. Avulsion fractures results due to s...
Clinicopathological Correlation of Leiomyoma in a Tertiary Care Centre: A Retrospective Study
Leiomyoma is the most common type of benign tumor of uterus and carry 70-80% of cumulative incidence in reproductive age group. Our study was conducted to analyse the clinicopathological correlation, spectrum of variants...
Preeclampsia is Associated with Elevated Iron and Ferritin in Third Trimester of Pregnancy: A Cross Sectional Observational Study from A Tertiary Center At Kolkata
Preeclampsia is one of the leading cause of maternal mortality during pregnancy. Generation of reactive oxygen species (ROS) in presence of catalytic amount of iron has been implicated into one of its pathogenesis. The o...
Comparison between Combination of Spinal and General Anesthesia with Plain General Anesthesia in Patients Undergoing Laparoscopic Gynaecological Surgeries
Aim and Objective: The present study was undertaken to compare the combination of spinal (SA) and general anesthesia (GA) with plain general anesthesia (GA) in terms of heamodynamic parameters, requirement of rescue anal...