Comparison of 60mg and 40mg doses of hyoscine butylbromide on labor outcomes at Moi teaching and referral hospital, Eldoret, Kenya
Journal Title: Indian Journal of Obstetrics and Gynecology Research - Year 2018, Vol 5, Issue 4
Abstract
Introduction Effects of 40mg of Hyoscine butylbromide HBB in reducing duration of active phase of labor are well documented However effects of 60mg have not been well studied despite the fact that it is often usedObjectives To compare the effect of 60mg and 40mg of HBB on the duration of laborMaterials and Methods A singleblind randomized controlled clinical trial was carried out at Moi Teaching and Referral Hospital from January to April 2014 At the onset of active phase of labor 45 cm they were randomized into two arms Those in the control arm received 40mg of HBB intravenously while those in the study arm received 60mg Information on progress of labor mode of delivery amount of blood loss and neonatal APGAR scores was recordedResults A total of 114 primigravid women were recruited into the study and randomized into the control arm n59 and study arm n55 The 40mg and 60mg arms were comparable for sociodemographic and obstetric characteristics Injection to delivery time was 340 223483 minutes in the 40mg arm and 305 253475 minutes in the 60mg arm a difference that is not statistically significant p0905 Seven 12 and five 9 of patients in the 40mg and 60mg arm respectively needed delivery via caesarean section p0602 5 minute APGAR scores were 97 in the 40mg arm and 98 in the 60mg arm p0727 Estimated blood loss was 300mls in the 60mg arm and 350mls in the 40mg arm p0152Conclusion Head to head 60mg of parenteral HBB is not superior to 40mg on their effects on duration of labor and fetomaternal outcomesKeywords Hyoscine Butylbromide Buscopan Labor
Authors and Affiliations
Anthony Wanjala, David Kaihura, Benjamin Chemwolo, Kays Muruka
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