Comparison of 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 Renal Scintigraphy in the Calculation of Relative Renal Function
Journal Title: Journal of Urological Surgery - Year 2020, Vol 7, Issue 2
Abstract
Objective: The aim of this study was to compare Tc-99m dimercaptosuccinic acid (99mTc-DMSA) renal cortical scintigraphy and Tc-99m diethylene triamine pentaacetic acid (99mTc-DTPA) and Tc-99m mercaptoacetyltriglycine (99mTc-MAG3) dynamic renal scintigraphy in the evaluation of relative renal function (RRF). Materials and Methods: Forty seven patients with renal cortical scintigraphy (with 99mTc-DMSA) and dynamic renal scintigraphy (with 99mTc-DTPA or 99mTc-MAG3) were included in this retrospective study. RRF obtained from 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 scintigraphies, clinical and demographic data were statistically analyzed. Results: There was a high correlation between 99mTc-DMSA renal cortical scintigraphy and dynamic renal scintigraphy (99mTc-DTPA or 99mTc-MAG3) in terms of RRF evaluation (r=0.981, p<0.001 and r=0.918, p=<0.001, respectively). While the Bland Altman plot showed an average difference of 3.30 between RRFs measured by 99mTc-DMSA and by 99mTc-DTPA, the difference between that with 99mTc-DMSA and 99mTc-MAG3 was 0.08. Conclusion: In conclusion, this study showed a high level of compliance between 99mTc-DMSA renal scintigraphy and dynamic renal scintigraphy (99mTc or 99mTc-MAG3) in the evaluation of RRF. Time loss, radiation exposed to the patients and economic losses are minimized with the use of a single method suitable for the purpose.
Authors and Affiliations
Fadime Demir, Mustafa Demir
Global Publication Outcomes in Retrograde Intrarenal Surgery and Turkiye’s Effectiveness: A Bibliometric Analysis between 1980 and 2019
Objective: Urinary system stone disease is a very common health problem that affects 2 to 3% of people and causes serious complications when it is not treated. The prevalence of renal stones has been increasing worldwide...
Extremely Rare Localization of Bladder Stone: Scrotal Bladder Hernia
Inguinoscrotal bladder hernia is rarely encountered relative to the common occurrence of inguinal hernia. Most patients are asymptomatic and diagnosed perioperatively; however, lower urinary tract symptoms along with swe...
Leydig Cell Tumor of the Testis: A Case with Incidental Diagnosis
Leydig cell tumors account for approximately 1-3% of adult testicular tumors. These tumors are the most common type of gonadal stromal tumors and most commonly seen in the third to sixth decades of life, and about 10% of...
Protective Effects of Oral Sirolimus Therapy against ESWL-induced Kidney Tissue Damage in Rats
Objective: In the present study, we aimed to investigate the short- and long-term protective effects of oral sirolimus therapy on extracorporeal shock wave lithotripsy (ESWL)-induced kidney tissue damage in an experiment...
Outcomes of Hypospadias Surgery Performed by Different Surgeons Under the Supervision of an Experienced Pediatric Urology Surgeon
Objective: Hypospadias is one of the most common congenital anomalies among males. Hypospadias repair is still a challenging issue due to its results and frequently seen complications. The most commonly used techniques a...