Comparison of Analgesic Efficacy of Peritubal Infiltration of Ropivacaine versus Ropivacaine and Morphine in Percutaneous Nephrolithotomy Under Fluoroscopic Guidance
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 5, Issue 11
Abstract
Background: The root cause of pain in percutaneous nephrolithotomy (PCNL) surgery is dilatation of renal capsule and parenchymal tract which is rich in pain-sensitive nerve fibers. A nephrostomy tube is retained which causes discomfort to the patients postoperatively. Local anaesthetics (LA) infiltrated into nephrostomy tract was done which decreases the pain scores significantly. Aim: The aim of this study is to compare the efficacy of spiritual infiltration of ropivacaine versus ropivacaine with morphine in PCNL surgeries under fluoroscopic guidance for post-operative analgesia. Materials and Methods: A prospective randomized, double-blinded study was compared the efficacy of peritubal infiltration of ropivacaine (0.25%) versus ropivacaine with morphine (0.1 mg/kg) under fluoroscopic guidance in 60 patients undergoing PCNL surgeries under general anaesthesia. They were allocated into two groups Group R - injection ropivacaine 0.25% and Group RM - injection ropivacaine 0.25% (10 mg) with morphine (0.1 mg/kg). Hemodynamic parameters, visual analog scale score, and any adverse effects were recorded. Results: The mean duration of analgesia was more in group RM than the patients in Group R. The mean dose of the analgesic requirement was less in group RM compared to Group R. Other hemodynamic parameters were comparable in both groups. Conclusion: Addition of morphine (0.1 mg/kg) to ropivacaine (0.25%) in peritubal infiltration offers a significant advantage over plain ropivacaine (0.25%) in terms of duration of analgesia and the need for rescue analgesia.
Authors and Affiliations
N Latha, S Bhuvana, M Saranya, Heber Anandan
Keywords
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