COMPARISON OF ANTI-DIABETIC AND ANTI-OXIDANT ACTIVITY OF WILD AND CULTIVATED VARIETY OF RAUWOLFIA SERPENTINA
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2017, Vol 10, Issue 12
Abstract
Objectives: About 80% of world populations are still dependent on herbal plants. Rauwolfia is also one of the wonder drugs of India, which is used since ancient time. It contains a variety of compounds with antioxidant activity and other health benefits. A wild variety of rauwolfia is became endangered due to indiscriminate use. Hence, its cultivation and collection have been started to complete the demand of rauwolfia. Therefore, the study was designed to evaluate and compare the in vitro antioxidant and antidiabetic activity of the wild and cultivated plant of rauwolfia. Methods: The methanolic extract of wild and cultivated plant was subjected to the DPPH and alpha-amylase inhibition activity for antioxidant and antidiabetic activity, respectively. Result: The study revealed that the wild and cultivated variety of Rauwolfia serpentina does not have a significant difference in their antidiabetic and antioxidant activities. Conclusion: On the basis of the in-vitro studies, it can be concluded that cultivated variety of the plant can be used as a substitute for a wild variety of R. serpentina.
Authors and Affiliations
Saveena Chauhan, Amrinder Kaur, Manish Vyas, Gopal L Khatik
Keywords
Related Articles
- EP ID EP605578
- DOI 10.22159/ajpcr.2017.v10i12.21287
- Views 130
- Downloads 0
PHARMACOGNOSTICAL STANDARDIZATION AND HIGH-PERFORMANCE THIN-LAYER CHROMATOGRAPHY FINGERPRINT OF ROOTS OF ANTHOCEPHALUS CADAMBA
Objective: Anthocephalus cadamba is a traditional medicinal plant which is valued for its benefits in the management of various ailments. The current study was aimed to provide requisite pharmacognostic details and high-...
IN VITRO CYTOTOXICITY ACTIVITY OF HYDROALCOHOLIC EXTRACT OF POLYHERBAL CHURNAM (COFRI) IN NORMAL LIVER AND KIDNEY CELL LINES
Objective: The objective of the study was to investigate the cytotoxic activity of hydroalcoholic extract of a polyherbal powder on Vero (normal kidney) and Chang (normal liver) cell lines. Methods: The cytotoxic effect...
ALPHA-AMYLASE AND ALPHA-GLUCOSIDASE INHIBITORY EFFECTS OF CALLIANDRA HAEMATOCEPHALA AND ITS POTENTIAL ROLE IN DIABETES MELLITUS
Objective: The global burden and the high prevalence of diabetes mellitus in India signify the importance of its control with effective measures. Particularly, intestinal alpha-amylase and alpha-glucosidase enzyme inhibi...
EPIDEMIOLOGICAL STUDY OF PREVALENCE OF ANEMIA AND ASSOCIATED RISK FACTORS IN A RURAL COMMUNITY; A HOME-BASED SCREENING
Objective: The prevalence of anemia is disproportionately high in developing countries due to poverty, inadequate diet, certain diseases, pregnancy and lactation, and poor access to health services. It is a risk factor f...
GAS CHROMATOGRAPHY-MASS SPECTROMETRY/MASS SPECTROMETRY ANALYSIS OF TERMINALIA CATAPPA L. NUT AND ANTIMICROBIAL ASSAY
ABSTRACTObjective: The present study was carried out with the main objective of studying Terminalia catappa nut phyto-constituents through GC-MS/MS, aswell as its antibacterial, antifungal activities.Methods: The T. cata...