COMPARISON OF ANTIMICROBIAL ACTIVITY OF LOCALLY PRODUCED SOAPS AND CONVENTIONAL MEDICATED SOAPS ON BACTERIAL ISOLATES FROMSKIN AND WOUND
Journal Title: World Journal of Pharmaceutical and Medical Research - Year 2018, Vol 4, Issue 10
Abstract
Antimicrobial activity of Locally made and Conventionalcustomized medicated soaps sold and widely used by the residents of Port Harcourt Metropolis. Rivers State, Nigeria was examined against some clinical bacterial isolates from skin surface and wound. Clinical isolates used were Staphylococcus aureus and Pseudomonas aeruginosa. the results showed that the test organisms were sensitive to the soap samples at different concentrations. As the concentration increased the zones of inhibition significantly increased. The results obtained showthat among the conventional customized medicated soaps, the highest effectiveness was carried out by Dettol (25mm) at 500mg/ml and Safeguard (24mm) at 500mg/ml against S. aureus and P. aeruginosa.In the category of locally made soaps, the red soap (LPRS) was discovered to be more effective on all the isolates (S. aureus,11.5mm and P. aeruginosa, 16.5mm) at 500mg/ml, as compared to locally produced black soap (LPBS) with this effectiveness S. aureus,8.5mm and P. aeruginosa, 12mm. The percentage of activity of the soaps on the test organisms showed that S. aureus displayed higher resistant to most of the soaps compared to P. aeruginosa. The Minimum Inhibitory Concentration (MIC) of the soaps with efficacy was found to be 125mg/ml on S. aureus and 250mg/ml on P. aeruginosa while the Minimum Bacteriocidal Concentration (MBC) was 250mg/ml for all theisolates.
Authors and Affiliations
Wemedo Samuel Amadi
Keywords
Related Articles
- EP ID EP665694
- DOI -
- Views 160
- Downloads 0
PREVALENCE OF POST PARTUM DEPRESSION AMONG THE PATIENTS REPORTING COMBINED MILITARY HOSPITAL CMH LAHORE USING EPDS SCALE
Background: To find out the prevalence of postpartum depression amongst the patients reporting combined military Hospital Lahore using Edinburg Postpartum Depression scale. Methods: This was a cross sectional, non-interv...
A STUDY OF VAMANDHAUTI (KUNJAL KRIYA) IN THE MANAGEMENT OF STHAULYA (OBESITY)
Ayurveda has been a proven science of life and an efficacious way of treatment of human diseases coupled with holistic approach in diagnosing diseases and thereafter providing an all-inclusive treatment of body and soul...
EVALUATION OF ANTIHYPERLIPIDEMIC AND ANTIDIABETIC ACTIVITY OF HYDRO-ALCOHOLIC EXTRACTS OF MORINGA OLIEFERA SEEDS IN HIGH FAT DIET INDUCED RAT MODEL
The aim of this study was to investigate the Antihyperglycemic and antihyperlipidemic activities of aqueous and ethanol extracts of seeds of Moringa oliefera in alloxan (ALX) induced diabetic rats. Diabetes was confirmed...
HOLISTIC APPROACH FOR THE PREVENTION OF AMLAPITTA
Amlapitta (Acid Peptic Disorder) is a very common emerging which is an abnormal pathological condition of pitta occurring due to indulgence in aahara, vihara and manasika bhava which are of incompatible combination, faul...
EVALUATION OF AROMATASE ACTIVITY IN PRE AND POSTMENOPAUSAL BREAST CANCER WOMEN
Cancer is a group of diseases that cause cells in the body to change and grow out of control. Most types of cancer cells eventually form a lump or mass called a tumor. Breast cancer is the second most common prevalent an...