COMPARISON OF ATROPINE INTRAVENOUS INFUSION VERSUS INTERMITTENT ATROPINE IN THE MANAGEMENT OF ORGANOPHOSPHORUS POISONING IN ICU
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 4
Abstract
BACKGROUND Comparison of atropine intravenous infusion with intermittent atropine in earlier recovery, atropinisation and complications of organophosphorus poisoning. It is very commonly seen in Indian population among patients admitted in hospital/ICU. Organophosphorus compounds bind irreversibly to the acetylcholinesterase in the plasma, red cells and cholinergic synapses in the CNS and the PNS. MATERIALS AND METHODS 50 patients of organophosphorus poisoning from July 2016 - February 2017 were included in study. RESULTS Atropine infusion is better as compared to intermittent atropine in the management of organophosphorus poisoning. CONCLUSION All patients on intravenous atropine infusion responded earlier and with less amount of atropine. Their pupillary dilatation, which is an (important criteria) for atropinisation occurred earlier than on intermittent atropine.
Authors and Affiliations
Khairunnisa Karamatullah Khan, Bushra Khanam, Shabahat Ali Siddiqui, Faeiz Khan
Keywords
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- EP ID EP451033
- DOI 10.18410/jebmh/2018/76
- Views 77
- Downloads 0
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