Comparison of Bispectral Index (BIS) of Halothane, Isoflurane, Desflurane and Sevoflurane at Equi-MAC end Tidal Concentration: A Randomized Control Study
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2018, Vol 5, Issue 12
Abstract
Background: MAC is most common method of titration of volatile anesthetics and BIS is used to measure the hypnotic effect of anesthetics. This study was undertaken to evaluate and compare the BIS value produced by different inhalational agents at their 1 MAC end tidal concentration. Method: 200 patients of ASA I II of either sex between 2050 years , for laparoscopic cholecystectomy were divided into 4 groups of 50 each and received either halothane, isoflurane, sevoflurane or desflurane. General anesthesia was administered using fentanyl, propofol, inhalational agents and vecuronium and maintained with 67% nitrous in oxygen. After achieving and maintaining 1 MAC for 15 min, BIS value were recorded for next 15 min at an interval of 1 min .Collected data was analyzed using ANOVA test. Results: At 1 MAC end tidal concentration mean BIS value for halothane was 57.0±3.51, for isoflurane 51.57±3.84, for sevoflurane value was 49.621± 3.82, and for desflurane BIS value 42.11±4.68, and difference among groups were statistically significant. Conclusion: At 1MAC, BIS values are agent specific and BIS value of halothane > isoflurane > sevoflurane > desflurane.
Authors and Affiliations
Neerja Banerjee
Keywords
Related Articles
- EP ID EP550276
- DOI 10.21088/ijaa.2349.8471.51218.5
- Views 72
- Downloads 0
A Comparative Evaluation of Thiopentone Sodium and Propofol as Inducing Agent for Caesarean Section
The success of anaesthesia in obstetrics depends largely upon surgical demand and maternofoetal well being. Hence the aim of anaesthesia is to provide safety and comfort to the mother, minimal neonatal depression and op...
A Comparative Study Between Ultrasound and Peripheral Nerve Stimulator Guided Supraclavicular Brachial Plexus Block in Adult Patients for Elective Upper Limb Orthopaedic Surgeries
Background: There are many advantages of ultrasound guided supraclavicular brachial plexus block over the peripheral nerve stimulator guided supraclavicular brachial plexus block. Ultrasonography allows the operator to v...
Comparative Study of Haemodynamic Response to Intubation with McCoy laryngoscope, Intubating LMA and Vividtrac® Videolaryngoscope in Controlled Hypertensive Patients
Laryngoscopy and intubation can result in significant haemodynamic response which is even more exaggerated in hypertensive patients. The magnitude of cardiovascular response is directly related to the force applied and d...
Comparative Study to Assess the Efficacy of Epidural Steroid Injection by Interlaminar and Trans-Foraminal Approach for Low Back Ache with Unilateral Lumbar Radicular Pain
Background: Interlaminar and trans-foraminal epidural steroid injections are commonly performed interventions in managing low backache with lumbosacral radicular pain.However, controversy exists to the superiority of one...
A Comparative Study of the Effect of Clonidine and Tramadol on Post- Spinal Anaesthesia Shivering during Intraoperative Period
Introduction: Region anaesthesia is widely used and a safe anaesthetic technique. Shivering is frequently a known complication during regional anaesthesia. Shivering is a potentially serious complication. There are vario...