Comparison of c- reactive protein, erythrocyte sedimentation rate, and leukocyte count as inflammatory markers
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH - Year 2014, Vol 6, Issue 7
Abstract
Background: Erythrocyte sedimentation rate, C-reactive protein, and leukocyte count are commonly used inflammatory markers. It is debatable whether each of these tests can be used individually or always these tests should be used in together. Objective: This study aimed to compare C-reactive protein, erythrocyte sedimentation rate and leukocyte count as inflammatory markers. Materials and Methods: This is an analytical comparative study; included 50 patients with different inflammatory disorders. Three blood samples were collected from each patient. Erythrocyte sedimentation rate was measured by Erythrocyte sedimentation rate fast detector, C-reactive protein was measured by immunofluorcent assay, and total and differential leukocyte counts were performed by automated haematology analyzer. Results: All patients were found to have high C-reactive protein and high erythrocyte sedimentation rate; while 19(38%) were had leuckocytosis, 25(50%) had normal leukocyte count, and 6(12%) had low leukocyte count. The correlation analysis showed a significant positive correlation between the C-reactive protein and each of total leukocyte count, absolute neutrophil count, absolute monocyte count, and absolute eosinophil count. Conclusion: As inflammatory markers, C-reactive protein and erythrocyte sedimentation rate can be used as interchangeably, while leukocyte count, when used, should be accompanied with either C-reactive protein or erythrocyte sedimentation rate.
Authors and Affiliations
Sheraz Alrashed Ibrahim and Elshazali Widaa Ali
Keywords
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