Comparison of Clonidine and Dexmedetomidine as an Adjuvant to 0.375% of Ropivacaine in Supraclavicular Brachial Plexus Block: A Prospective Study
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 4
Abstract
Background and Objective: Various adjuvants are added to local anesthetic to prolong the duration and faster the onset time of sensory and motor block and increase the quality of various types of peripheral nerve blocks and in local infiltration also. Presented study was conducted in upper limb surgery to evaluate and compare the effect of addition of clonidine and dexmedetomidine in ropivacaine as an adjuvant. Methodology: This prospective observational study was planned insixty ASA Grade I and II patients scheduled for upper limb surgeries under supraclavicular brachial plexus block and were randomly divided in to two equal groups, 30 patients in each. Group RC(n=30) received clonidine 1ug/kg (1ml) and Group RD(n=30) received dexmedetomidine 1ug/kg (1ml)added to ropivacaine 0.375 % (39 ml), total 40 ml volume was prepared and injected by using paresthesia with blind technique of supraclavicular block. Thereafter, onset time of sensory, motor block, duration of sensory, motor block, duration of analgesia, sedation score, grade of bleeding during surgery, systemic side effects and variation in hemodynamic parameters at different time intervals were studies in both the group. Results: The duration of sensory and motor block and duration of analgesia was significantly prolonged in RD group as compare to RC group (p value 0.001) but there was no statistically significant difference in onset of sensory and motor block between two groups and sedation score was better in RD group as compare to RC group. Conclusion: Dexmedetomidine is better adjuvant compare to clonidine added to ropivacaine 0.375% in supraclavicular brachial plexus block enhanced the duration analgesia, sensory and motor block and also quality of anesthesia
Authors and Affiliations
Dr Kamlesh K Shekhawat
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