Comparison Of Cytomorphological Details In Liquid Based Cytology And Conventional Cytology In Fine Needle Aspirates Of Pleomorphic Adenoma
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH - Year 2018, Vol 10, Issue 3
Abstract
Introduction: Liquid based cytology which is at present the standard protocol in cervical cytology samples is also being increasingly used for evaluation of non-gynecological specimens. There are few studies comparing LBC with conventional smears (CS) in salivary gland (SG) fine-needle aspiration biopsies (FNAB) and most of them have been done on Thin Prep. This study compares the cytomorphological details of Sure Path and conventional cytology in cases of pleomorphic adenoma. Aim: The aim of our study is to compare conventional smears and liquid based cytology (SurePath) in FNA of Pleomorphic adenoma in terms of cytomorphological details, adequacy and ease of interpretation. Materials and Methods: We conducted a prospective observational comparative study which included 47 cases of Pleomorphic adenoma. Both CS and LBC (SurePath) smears were prepared as per standard protocols and examined. Results and conclusion: In terms of adequacy and cellularity, conventional smears were better than LBC. Diagnostic accuracy of both the techniques in cellular cases however was comparable. Ease of interpretation was better with conventional smears due to abundant chondromyxoid stroma, an important clue in the diagnosis of pleomorphic adenoma. Nuclear details and background were better in LBC as compared to CS.
Authors and Affiliations
1Shweta Katiyar, 1,*Madhu Kumar, 1Madhu Mati Goel, 1Ashutosh Kumar ., Veerendra Verma and 2Singh, H. P .
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