Comparison of dexmedetomidine and clonidine as an adjuvant to levobupivacaine in supraclavicular brachial plexus block

Journal Title: International Journal of Medical Research and Review - Year 2017, Vol 5, Issue 4

Abstract

Introduction: There are always efforts to find better and safer local anaesthetics along with adjuvants for supraclavicular brachial plexus block. Levobupivacaine has strongly emerged as a safer alternative for regional anaesthesia than its racemic sibling bupivacaine. Alpha 2 agonists are combined with local anaesthetics to improve the quality of regional anaesthesia. Method: A prospective randomized study was carried out which included 60 adult patients between the ages of 18-65 years of ASA grade I and II who underwent upper limb orthopaedic surgeries. Group A received 30 ml of 0.5% levobupivacaine with 150µg of clonidine and Group B received admixture of 30 ml of 0.5% levobupivacaine with 100 µg of Dexmedetomidine. Onset, duration of sensory and motor blockade and duration of analgesia were observed. Results: Duration of postoperative analgesia in group A was 14.36±0.36 minutes and in group B was 16.90±2.29 minutes. Hence from the above observation, the duration of analgesia in group B is longer than group A which is statistically highly significant (p<0.001). Conclusion: Dexmedetomidine as an adjuvant 0.5% levobupivacaine is more effective in prolonging the duration of sensory and motor block and post operative analgesia compare to clonidine as an adjuvant to 0.5% levobupivacaine.

Authors and Affiliations

Amar Parkash Kataria, Vishal Jarewal, Gurpal Singh, Joginder Pal Attri

Keywords

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  • EP ID EP271308
  • DOI 10.17511/ijmrr. 2017.i04.05
  • Views 108
  • Downloads 0

How To Cite

Amar Parkash Kataria, Vishal Jarewal, Gurpal Singh, Joginder Pal Attri (2017). Comparison of dexmedetomidine and clonidine as an adjuvant to levobupivacaine in supraclavicular brachial plexus block. International Journal of Medical Research and Review, 5(4), 399-404. https://europub.co.uk/articles/-A-271308