COMPARISON OF DIAGNOSTIC EFFICACY BETWEEN CONVENTIONAL CYTOPATHOLOGY & LIQUID BASED CYTOLOGY IN THYROID FNA SMEARS USING BETHESDA SYSTEM OF REPORTING
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 9
Abstract
BACKGROUND Conventional cytology is a minimal invasive procedure used for all palpable lesions. Liquid Based Cytology (LBC) is a modified technique used in the current study. The objective of the study is to find out the diagnostic accuracy of Liquid Based Cytology (LBC) as compared to Conventional FNAC (CP) in thyroid cases. MATERIALS AND METHODS A hospital-based cross-sectional study was conducted in eastern India. All thyroid swelling cases referred for FNAC were included. Results were captured with general profile of the patients. Data was analysed for diagnostic accuracy using Stata. RESULTS Concordance rate between LBC and CP was 70.8% (highest for malignancy (92.8%)). Sensitivity CP and LBC was 82.4(56.6 – 96.2) and 75.0% (47.6 – 92.7) respectively, and specificity was 100.0(93 – 100.0) and 97.1% (74.6 – 97) respectively. PPV and NPV for CP were 100.0% (76.8 – 100.0) and 94.4% (84.6 – 98.8) respectively and for LBC were 92.3% (64.0 – 99.8) and 89.2% (74.6 – 97.0) respectively. LR+ in LBC was found to be high (25.5). CONCLUSION LBC can help ruling in malignancy in thyroid but FNAC (CP) remains the procedure of choice.
Authors and Affiliations
Swagatika Agrawal, Pranita Mohanty, Raghumani Mohanty
Keywords
Related Articles
- EP ID EP474694
- DOI 10.18410/jebmh/2018/159
- Views 64
- Downloads 0
DISTAL RENAL TU
PRESENTATION OF CASE We report hypokalaemic quadriparesis presenting in a 45- year-old woman. Evaluation of the case revealed that hypokalaemic quadriparesis was secondary to underlying distal RTA (known as type 1 RTA),...
SUPRAPATELLAR VERSUS INFRAPATELLAR TIBIAL NAIL INSERTION- A PROSPECTIVE, RANDOMISED CONTROL PILOT STUDY
BACKGROUND The standard for treating tibial shaft fractures are by intramedullary nails currently. After the procedure, one of the most frequent complication is knee pain, after consolidation even more chronically. Chron...
EXTENDED INTRALESIONAL EXCISION IN GCT OF DISTAL END OF RADIUS- A PROSPECTIVE STUDY
BACKGROUND Recurrence is a common problem in GCT. A treatment modality without sacrificing the joint function and without compromising the tumour clearance is the necessity. MATERIALS AND METHODS Distal end radius GCTs t...
TUBERCULOUS LUPUS OF NOSE: INTERESTING PRESENTATION INVOLVING FATHER AND SON
Cutaneous tuberculosis, although a disease of the past, is occasionally seen especially in the developing world. It can present in at least seven morphological types. 1 Lupus vulgaris is the commonest morphological prese...
FOREIGN BODY LOWER RESPIRATORY TRACT: SUSPICION SCORING SYSTEM
Foreign body aspiration accidents are due mainly to carelessness of the parents to give children unsuitable articles or inedible objects to eat or play with. Bronchoscopists have removed variety of objects from the trach...