Comparison of Drug Resistance pattern under supervised Vs unsupervised treatment of Tuberculosis
Journal Title: National Journal of Research in Community Medicine - Year 2017, Vol 6, Issue 4
Abstract
Background: The prevalence of drug resistance was higher in areas with poor tuberculosis control. Resistance to Anti tuberculosis treatment was found in all 35 countries and regions surveyed. Objective: To Compare of Drug Resistance pattern in cases under supervised vs unsupervised treatment. Study design: Hospital based study. Setting: Department of Pulmonary Medicine, Motilal Nehru Medical College (MLNMC), Allahabad, (U.P) India. Participants: 52 patients. Sampling: Purposive sampling method. Results: Out of 52 patients 23(44.23 %) were relapse, 22(42.30 %) were treatment failure and 7(13.46) were defaulter. Treatment failure cases were more in unsupervised group 28.84% compare with supervised group 13.46%, relapse were more in supervised group 26.9%, as compared to unsupervised group 17.3% and defaulter were more in unsupervised group 11.5%, as compare to supervised group 1.96%. nine patients (17.6%) who took supervised treatment previously were susceptible to all tested drug as compare to unsupervised group in which 3(5.9%) cases were susceptible to all tested drug. 6(11.76%) cases were single drug resistance in supervised group as compared to unsupervised in which 7(13.72%) cases were single drug resistance. Poly resistance were more 12 (23.53%) in unsupervised group as compare to supervised group in which 4(7.84%) cases were poly resistance. Multi drug resistance cases were more 7(7.84%) cases in unsupervised group as compare to supervised group in which 3(5.90%) cases were multi drug resistance Conclusion: It was concluded that supersized strategy was superior to unsupervised treatment in controlling the tuberculosis infection and in preventing the emergence of drug resistance tuberculosis
Authors and Affiliations
Ashish Kumar Gupta, Tariq Mahmood, Mohd Haroon Khan
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