Comparison of Efficacy of Morphine and Sodium Diclofenac Suppository for Analgesia after Appendectomy and Inguinal Hernia Surgery
Journal Title: Asian Journal of Research in Medical and Pharmaceutical Sciences - Year 2017, Vol 1, Issue 1
Abstract
Introduction: Pain is caused after tissue damage, it is one of the problems of clinical cares after surgery. Analgesia is important for the recovery acceleration of patients after surgery. In this study, the efficacy of morphine and diclofenac sodium suppository for analgesia after appendectomy and inguinal hernia surgery were evaluated. Methods: This study is a double-blind clinical trial study, about 75 patients (Range age 18-70years) with appendicitis and inguinal hernia were assessed. They were randomized into three equal groups. The pain score of patients, according to Visual Analogue Scale (VAS), was measured by scale ruler of 0-10 cm. Results: The mean visual analogue scores of pain were in the morphine group respectively 4.56, 4.40, 3.68, and 3.36 for2, 6, 12, 24 hours. Also, mean scores were in the group receiving diclofenac suppository respectively 4.36, 3.84, 3.12, 2.44 and in the control group 6.52, 6.68, 6.28, and 5.84 for these hours. The VAS mean scores were significantly lower in the both groups receiving diclofenac and morphine suppository Compared to control group (p<0.001). Conclusion: Sodium diclofenac suppository caused more analgesia than morphine suppository after appendectomy and inguinal hernia surgery.
Authors and Affiliations
Ghodrat Akhavan Akbari, Ahmad Ghazi, Tiba Mirzarahimi
Assessment of the Microbiological Safety of Potable Water from Rural Settlements in Owo Local Government Area of Ondo State, Nigeria
Access to quality drinking water is a major problem in rural settlements in Owo Local Government Area (L.G.A.) of Ondo State, Nigeria where surface and ground water sources (streams and wells) used for drinking are locat...
Improving Wound Dressing Techniques and Infection Control through Support from International Non-Governmental Organizations in Sub-Sahara Africa
The script is a first-hand report and reviews of activities that ensures high and standard quality wound care in resource limited health facility by intervention from medical projects of International Non-Governmental su...
Phytochemical Screening, Acute and Sub-chronic Toxicity Studies of Aqueous Stem Bark Extract of Ficus polita
Ficus polita Vahl is a tropical African evergreen shrub or small tree belonging to the family Moraceae, and usually growing up to 15 metres tall. Extracts from different part of the plant had been demonstrated to exhibit...
Acute and Chronic Effects of Methanolic Extract of Teucrium polium on Blood Parameters and Histopathology of Liver and Kidney in Female Rats
Background: Teucrium polium L. is a medicinal plant largely used traditionally in folk medicine in Algeria, locally named: Khayata. It is effective in the treatment of various diseases. Methods: The Total Polyphenol and...
Seroprevalence of Herpes Simplex Virus Type 2 (HSV-2) among Pregnant Women Accessing Antenatal Care in a Tertiary Healthcare Facility in Central Nigeria
Herpes simplex virus type 2 (HSV-2) infections is one of the most common sexually transmitted infections worldwide. Due to lack of documented HSV-2 studies among pregnant women in the study area, a detailed cross-section...