COMPARISON OF EFFICACY OF PROPOFOL & KETAMINE AND PROPOFOL & FENTANYL IN PATIENTS UNDERGOING SURGERY.
Journal Title: IJAR-Indian Journal of Applied Research - Year 2018, Vol 8, Issue 12
Abstract
Introduction: An ideal anaesthesia always provides pleasant induction, minimal adverse conditions, inevitable loss of consciousness and rapid, smooth recovery of protective reflexes. The combination of Propofol, Fentanyl and Ketamine provides complete and balanced anaesthesia with advantages such as high potency, lower doses and fewer side effects. This study designed to compare the efficacy of propofol with fentanyl and propofol in combination with ketamine in patients undergoing surgeries. Materials and Methods: The present comparative study contains 120 cases undergoing various surgeries belonged to ASA grade I and II of both sexes and age between 2nd to 6th decades were recruited. Based on administered drug combinations cases were divided in to two groups i.e. group 1 administered with propofol & ketamine and group 2 administered with propofol and fentanyl. Oxygen saturation (SpO2), Heart rate, Systolic blood pressure (SBP), diastolic blood pressure (DBP) and respiratory rate was noted for all the participants before the surgical procedure and for every 5min after a surgical procedure. Results: The onset of induction was rapid in group 1 cases than group 2 cases. The mean pulse rate was significantly decreased after induction at 1 min, 5 min, 10 min, and 20 min. whereas in group 2, the mean pulse rate was decreased at 1 min and increased at 5 min, 10 min and 20 min. The mean respiratory rate and oxygen saturation also stable in both groups. Conclusion: The drug combination of propofol & ketamine and propofol & fentanyl are efficient in the maintenance of respiratory rate, oxygen saturation and haemodynamic stability. In this regard, drug combination of propofol & ketamine are best drug choice in surgical practice. Acceptance of propofol & ketamine is higher than propofol & Fentanyl.
Authors and Affiliations
Dr. Badri Narayana Chigullapally
Keywords
Related Articles
- EP ID EP452544
- DOI -
- Views 27
- Downloads 0
Spinal Tuberculosis: An Unusual Presentation
We report a rare case of pre vertebral cold abscess of dorsal spine in a 40 yr old man, who presented with neck swelling. He had a soft swelling in the right side of neck, progressively increasing. He also had imbalance...
Comparative Analysis of Lip prints, Finger prints and Blood Groups: A Cross-sectional Study.
In forensic identification the mouth allows for a myriad of possibilities. Due to distinctive features, dental identification plays a key role to positively identify an individual.Sulci laborium present on the labial muc...
Neonatal Radiology Apps at the at point of care & training
The Neonatology is a very challenging branch with almost zero scope of error in newborn care due to inherent attributes of the neonates. Hence, timely establishment of the exact diagnosis becomes impe-ra tive. It is esse...
STOCK MARKET INTERDEPENDENCE : EVIDENCE FROM INDIAN AND THE SINGAPORE STOCK MARKET
In this research, the researcher is to explore the nature of the association and the possible existence of a short-run and long-run relationship between the stock-market indices of India and the Singapore. The idea behin...
PERCEPTION AND KNOWLEDGE OF VAGINAL DISCHARGE AMONG WOMEN IN RURAL SETTING IN ALIGARH
The complaint of abnormal vaginal discharge is very common.An excessive degree of vaginal secretion is not necessarily pathologically infected, but could be hormonal. The aim of this study was to nd out the perception a...