Comparison of Efficacy of the Anti-inflammatory Effect of Topical 0.1% Dexamethasone Sodium and Topical 0.05% Difluprednate Eye Drops after Small Incision Cataract Surgery
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2019, Vol 6, Issue 10
Abstract
Aims: The study aims to compare the efficacy of the anti-inflammatory effect of 0.1% dexamethasone sodium and 0.05% difluprednate eye drops after small incision cataract surgery (SICS). Study Design: A prospective, randomized, and clinical study was conducted on patients. Place and Duration of Study: This study was conducted in the Department of Ophthalmology, VCGS Government Medical College, Srinagar, Uttarakhand, between December 2017 and November 2018. Materials and Methods: This study included two groups of 40 patients each (a total of 80 patients). 40 patients in Group A were randomly started on 0.1% dexamethasone eye drops postoperatively and another 40 patients in Group B were randomly started 0.05% difluprednate eye drops postoperatively. Response to the therapy was recorded on day 1, 7, and 40 on the parameters of post-operative anterior chamber reaction and post-operative visual acuity, and the results were compared. Results: All results were correlated with final visual outcome, and post-operative flare, which showed 0.05% difluprednate, is clinically and statistically more effective in early post-operative period than 0.1% dexamethasone sodium to control inflammation in uneventful SICS. Conclusions: After the comparison of the data in both the groups, the patients started on 0.05% difluprednate eye drops postoperatively showed better response to therapy (P < 0.0001) with respect to the parameters of best-corrected visual acuity and post-operative flare as compared to the patients started on 0.1% dexamethasone sodium eye drop therapy postoperatively, indicating that 0.05% difluprednate eye drops have a better anti-inflammatory effect.
Authors and Affiliations
Prateek Koul, Abhishek Padha, Swati Sharma
Keywords
Related Articles
- EP ID EP483655
- DOI -
- Views 111
- Downloads 0
Bacteriological Profile and Antibiotic Susceptibility Pattern of the Isolates among the Neonatal Septicemia in Northeast India
Background: Bacterial resistance to antibiotics was a global problem. Multidrug-resistant bacteria causing neonatal septicemias were increasing in the world. It was difficult to compare the bacterial profile and antibiot...
Effects of Oral Submucous Fibrosis on Auditory Tube Function: A Case–control Study
Background: Oral submucous fibrosis (OSMF) is a precancerous condition, recognized as collagen disease with resemblance to localized scleroderma. The study is to analyze the middle ear pressure of OSMF patients of variou...
Mortality Pattern of Children Admitted In Rural Medical College
Introduction: Childhood mortality is a sensitive health indicator and its pattern in the given area is important for policymaking. Materials and Methods: This is a retrospective study done using hospital records. Deaths...
Pelvic Floor Disorders Following Hysterectomy for Benign Conditions of Uterus and Endometrial Carcinoma - A Long-term Follow-up Study
Background: Vaginal vault prolapse occurs usually as a consequence of prior hysterectomy. Other causes are inborn or age dependent insufficiency of soft tissue, damage to the pelvic floor during and after childbirth and...
Usefulness of Pre-operative High-resolution Computed Tomography in Middle Ear Cholesteatoma
Introduction: Cholesteatoma is traditionally diagnosed by otoscopic examination and treated by exploratory surgery. The need for imaging in an uncomplicated case is contentious. The study assesses the usefulness of a pre...