Comparison of intranasal versus intravenous pethidine for pain relief after cesarean section
Journal Title: Zahedan Journal of Research in Medical Sciences - Year 2011, Vol 13, Issue 6
Abstract
Background: Intranasal route administration of opioid drugs has been shown to be an alternative treatment method without major side effects. In this study we evaluated the intranasal (IN) versus intravenous (IV) pethidine for postoperative pain relief after cesarean section. Materials and Method: In this clinical trial , 126 women undergoing elective cesarean section with general anesthesia using thiopental sodium 5 mg/kg, succynylcholine 1.5 mg /kg, then O2/N2O with 50/50 ratio, halothane 0.5 MAC, atracurium 0.2 mg /kg and fentanyl were entered into the study. Parturients were randomized in to two groups receiving IN pethidine (1mg/kg, n=63) or IV pethidine (1mg/kg, n=63) in recovery room. Pain intensity, incidence of nausea and vomiting and systolic blood pressure were recorded after pethidine administration and then every half an hour for 4 hours. Data analyzed with independent student t-test using SPSS software. Results: The mean visual analogue scale score in IV group was less than IN group at first two hours after pethidine administration. No significant difference in the incidence of nausea and vomiting was found between two groups. There was a significant decrease in mean systolic blood pressure in IV group compared with IN group at all the times (P<0.05). Conclusion: Although, IN pethidine was less effective on post cesarean pain relief, it seems to be an interesting alternative route for those who had no intravenous access, or had an allergy to morphine and unabale oral intake. [ZJRMS, 2011; 13(6):8-12] Keywords: Pethidine, postoperative pain, cesarean
Authors and Affiliations
Mitra Jabalameli, Shahnaz Aram, Masood Shahbazi, Maryam Parvaresh, Sharareh Taheri
Keywords
Related Articles
- EP ID EP86079
- DOI -
- Views 153
- Downloads 0
Prevalence of asthma symptoms and allergic diseases with ISSAC method in children, Shiraz 2009
Background: Asthma is the most important chronic disease in children and the most common cause of school absenteeism. Its prevalence has been raised due to increased environmental and industrial. This study were designed...
وي‍ژگي¬هاي نانوساختار لايه سطحي در برخي از باكتري¬هاي بيماري¬زا
زمینه و هدف: لایه سطحی (Surface Layer) قسمتی از انولوپ سلولی است که در باکتری¬ها و آرشی¬ها دیده می¬شود. لایه سطحی یک ساختار تک لایه-ای است که از زیرواحدهای پروتئینی یا گلیکوپروتئینی به¬وجود آمده است. لایه سطحی خارجی¬ترین...
Connective tissue diseases mimicking multiple sclerosis
Background: Connective tissue diseases (CTD) can involve nervous system. Diagnosis and differentiation from multiple sclerosis (MS) can be difficult especially when the disease presented by symptoms and signs related to...
Which Health Literacy Skills Are Associated with Smoking?
null
The Field Practices of Lambdacyhalothrin and Deltamethrin Insecticides Against Adult Mosquitoes of Anopheles stephensi as the Main Vector of Malaria: Residual Effects
Background: Various chemical control methods have adopted in anti-malaria interventions. Indoor residual spraying (IRS) has been proven as a candidate in elimination program. On the other hand, resistance to multiple ins...