Comparison of Intraperitoneal Instillation of Bupivacaine and Bupivacaine with Dexmedetomidine for Postoperative Analgesia after Laparoscopic Surgery
Journal Title: International Journal of Innovative Research in Medical Science - Year 2016, Vol 1, Issue 7
Abstract
Background and aims: Post-operative pain is one of the major problems in laparoscopic surgeries, wherein lack of control on it has many side-effects such as tachycardia, hypertension, myocardial ischemia, decreased alveolar ventilation, and prolongs hospital stay. We have evaluated the antinociceptive effects of intraperitoneal instillation of bupivacaine plain and bupivacaine with dexmedetomidine in patients undergoing laparoscopic surgeries. Materials: A total of 100 patients belonging to American Society of Anesthesiologist physical status I-II, in the age group of 18-70 years, of either sex undergoing laparoscopic surgery under general anesthesia were divided in two groups. Group B received bupivacaine (0.25%) 40 ml intraperitoneal instillation and group BD received bupivacaine (0.25%) 40 ml with dexmedetomidine 1μg/kg intraperitoneal instillation before removal of trocar at the end of surgery. The quality of analgesia was assessed by visual analogue scale (VAS) and sedation by Ramsey sedation score. Time to first request of analgesia, total dose of analgesic in first 24 hrs and adverse effects were also noted. Results: There was statistically significant difference in VAS at six hours after surgery in group BD (3.14±0.40) compared to group B (4.12±0.82) up to 24 hours with higher sedation score for first six hours. The time to first rescue analgesic was significantly higher in group BD (7.76 hours) compared to group B (5.92 hours) and less total analgesic consumption(mg) in group BD (1.9) compared to group B (2.21). Conclusion: Intraperitoneal instillation of bupivacaine with dexmedetomidine significantly prolong the duration of analgesia as compared to intraperitoneal instillation of bupivacaine alone without any side effects.
Authors and Affiliations
Dr. Hiteshkumar S. Patel, Dr. Nilesh Solanki, Dr. Bharat Shah Dr. Namrata, Dr. Rutu Shah
Keywords
Related Articles
- EP ID EP181323
- DOI -
- Views 91
- Downloads 0
MAURIAC SYNDROME WITH CELIAC DISEASE: RARE ASSOCIATION
Growth failure in type 1 Diabetes Mellitus can occur for several reasons. Mauriac syndrome is a rare cause of severe growth failure in type 1 Diabetes Mellitus.The classical severe presentation of Celiac Disease rarely o...
Attitude of Nursing Students towards Computer Assisted Learning in a Selected Nursing College, Hafar al Batin, Saudi Arabia
Computer knowledge and skills are becoming essential components technology in nursing education. The use of technology has become a central part of the practice of professional nursing. Graduates of nursing programs toda...
Effectiveness of Educational and Behavioral Models in the Reduction of Inappropriate Antibiotic Prescribing in United States Health Delivery Settings
Inappropriate antibiotic prescribing represents the most avoidable cause of resistance to antimicrobial drugs (CDC, 2015). As prevention constitutes the core principles of public health, any intervention addressing inapp...
Does an Immersive, Technology-Enhanced Course Design Improve Nursing Student's Learning Experience and Pathophysiology Exam Results?
Aim: This study evaluated the impact of an innovative technology-enhanced immersive approach to course design on second-year undergraduate nursing student’s learning experience and exam performance. Background: Two case-...
Genetic Disorders a Bird View
Impairment in an individual DNA leads to the occurrence of genetic disorders. There are different factors which leads to the alteration in gene, chromosome. The alteration addition or deletion of particular gene or segme...