Comparison of Intraperitoneal Instillation of Bupivacaine and Bupivacaine with Dexmedetomidine for Postoperative Analgesia after Laparoscopic Surgery
Journal Title: International Journal of Innovative Research in Medical Science - Year 2016, Vol 1, Issue 7
Abstract
Background and aims: Post-operative pain is one of the major problems in laparoscopic surgeries, wherein lack of control on it has many side-effects such as tachycardia, hypertension, myocardial ischemia, decreased alveolar ventilation, and prolongs hospital stay. We have evaluated the antinociceptive effects of intraperitoneal instillation of bupivacaine plain and bupivacaine with dexmedetomidine in patients undergoing laparoscopic surgeries. Materials: A total of 100 patients belonging to American Society of Anesthesiologist physical status I-II, in the age group of 18-70 years, of either sex undergoing laparoscopic surgery under general anesthesia were divided in two groups. Group B received bupivacaine (0.25%) 40 ml intraperitoneal instillation and group BD received bupivacaine (0.25%) 40 ml with dexmedetomidine 1μg/kg intraperitoneal instillation before removal of trocar at the end of surgery. The quality of analgesia was assessed by visual analogue scale (VAS) and sedation by Ramsey sedation score. Time to first request of analgesia, total dose of analgesic in first 24 hrs and adverse effects were also noted. Results: There was statistically significant difference in VAS at six hours after surgery in group BD (3.14±0.40) compared to group B (4.12±0.82) up to 24 hours with higher sedation score for first six hours. The time to first rescue analgesic was significantly higher in group BD (7.76 hours) compared to group B (5.92 hours) and less total analgesic consumption(mg) in group BD (1.9) compared to group B (2.21). Conclusion: Intraperitoneal instillation of bupivacaine with dexmedetomidine significantly prolong the duration of analgesia as compared to intraperitoneal instillation of bupivacaine alone without any side effects.
Authors and Affiliations
Dr. Hiteshkumar S. Patel, Dr. Nilesh Solanki, Dr. Bharat Shah Dr. Namrata, Dr. Rutu Shah
Keywords
Related Articles
- EP ID EP181323
- DOI -
- Views 65
- Downloads 0
Efficacy and Safety of a Combination of Levocetirizine and Phenylephrine in the Treatment of Allergic Rhinitis and Eustachian Tube Dysfunction
Introduction: Allergic Rhinitis (AR) and Eustachian Tube Dysfunction (ETD) are commonly seen in adults. Treatment options for AR and ETD is directed towards multiple symptom relief. A FDC of Levocetirizine, an anti-hista...
Vertebral Artery Arising From the Aortic Arch - A Study of Its Incidence
The vertebral artery (VA) is clinically described as the first branch of the ipsilateral subclavian artery. However, multiple variations in the origin of that vessel have been reported in the literature. This variation i...
Multicentric Histocytosis Mimicking Histoid Leprosy- A Case Report
Multicentric reticulohistiocytosis (MRH) is a very rare systemic disease with variable phenotypic presentation having predominant joint and cutaneous manifestations most commonly affecting women in middle age. The diagno...
Ponticulus Posticus- The “Aching” Bridge
The Ponticulus posticus is a bony bridge located in the posterior arch of the atlas. It houses the passage of the vertebral artery. Its presence has been associated with development of cervical pain, migraine and diplopi...
Study of Ropivacaine Block to Reduce Post- Operative Pain after Strip Harvesting, And Relation of Width of Strip to Post-Operative Pain
Introduction - Strip method of follicle harvesting has great advantage but Post-operative pain as well as fear of pain is commonest complain of this surgery. Severity of post-operative pain is in direct relation to width...