Comparison of intravaginal misoprostol alone and in combination with intracervical Foley’s catheter for termination of second trimester pregnancy- 3 years study at a tertiary care hospital
Journal Title: Perspectives In Medical Research - Year 2016, Vol 4, Issue 1
Abstract
Introduction: Termination of pregnancy in second trimester is one of the greatest challenges in modern obstetrics practice and is more risky than during first trimester. Now the main concern of the obstetrician is to provide the most effective, safest, and cost effective regimen with least or no complications. Objectives: To compare the effectiveness and safety of misoprostol alone and its combination with intracervical Foley’s catheter for second trimester termination of pregnancy. Material and Methods:100 women of 14-28 weeks of pregnancy were enrolled for termination for any indication and were randomized into two groups. Group I (study group): received 200 mcg of misoprostol 6 hourly and intracervical Foley’s catheter. Group II (control group): received only 200 mcg of misoprostol 6 hourly, upto a maximum five doses. The outcomes are measured in terms of success rate of abortion within 48 hours, induction to delivery interval and maternal side effects Results: The induction to abortion interval was 13.84±5.37 hours in the combined group compared to 22.68±4.82 hours in the misoprostol group (P value<0.001) with success rate of 90% in the combined group and no major complications reported. Conclusion: Use of intracervical Foley’s catheter improves the efficacy of vaginal misoprostol for termination of midtrimester pregnancy with shorter induction to delivery interval with no significant increase in side effects.
Authors and Affiliations
Subha Ranjan
Keywords
Related Articles
- EP ID EP299175
- DOI -
- Views 131
- Downloads 0
A clinico- mycological appraisal of Dermatophytosis
Introduction: Cutaneous fungal infections have been reported worldwide as one of the most common dermatological disease in clinical practice. In spite of therapeutic advances in the last decade, the prevalence of cutaneo...
Impact of Endosulfan on Male Reproductive functions - a review
ntroduction: Endosulfan is an organochlorine insecticide and acaracide used to control a broad range of insect and arthropod pests on a wide variety of crops in many agrosystems. It can cause acute and chronic toxicity....
Pleomorphic adenoma of the minor salivary gland in parapharyngeal space - A rarity: Case report
Introduction: Pleomorphic adenoma (PA) can be defined as a benign mixed tumor composed of epithelial and myoepithelial cells arranged in various morphological patterns, demarcated from surrounding tissues by a fibrous ca...
Cardiac biomarkers and their association in diagnosis and prognosis of Acute Coronary Syndrome
Introduction: Coronary artery disease (CAD) is a modern epidemic, closely following infectious disease in the Indian subcontinent. Indians are likely to account for at least 33.5% of total coronary heart disease (CHD) re...
Parenteral iron sucrose as an alternative to packed cell transfusion in moderate to severe anaemia in pregnancy
Introduction: Iron deficiency anaemia remains the most common medical disorder in pregnancy in the developing world, with the burden of disease impacting on both the mother and the new born. Packed cells\blood transfusio...