Comparison of intravitreal triamcinolone and posterior subtenon triamcinolone in diffuse diabetic macular edema

Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2018, Vol 4, Issue 1

Abstract

Aim To assess the efficacy and complications of the intravitreal injection of Triamcinolone Acetonide IVTA as compared to posterior subtenon injection of triamcinolone PST for the treatment of diabetic macular edemaMaterials and Methods Twenty four patients with type II diabetes having diabetic retinopathy with macular edema were recruited One eye of each patient was assigned to 4mg IVTA and the other eye was given 40 mg PST Before and one three and six months after treatment we measured visual acuity as well as thickness of the macula with optical coherence tomography OCT and intraocular pressure IOPResults In the IVTA group a reduction in foveal thickness of 150micro was observed p 0012 at 3 months compared to baseline A reduction of around 70 microns was observed in the PST group which was not statistically significant p 0290 In the IVTA group the mean visual acuity increased from 10480512 at baseline to 07070552 at 6 months which was statistically significant p 0001 In the PST group the mean visual acuity improved from 0797 0425 at baseline to 0727 0448 after 6 months with visual improvement maintained in 9 eyes 45 throughout the study period IOP rise in IVTA group was not statistically significant whereas in the PST group it became statistically significant However IOP rise lost its significance at 6 months p 009 owing to treatment with antiglaucoma medicationsConclusion Both IVTA and PST can be used as effective treatment options for diabetic macular edemaKeywords Diabetic macular edema Foveal thickness Intravitreal injection Posterior subtenon injection Triamcinolone acetonide Visual acuity

Authors and Affiliations

P. S. S. Soujanya, Sikander A. K. Lodhi

Keywords

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  • EP ID EP474186
  • DOI 10.18231/2395-1451.2018.0013
  • Views 101
  • Downloads 0

How To Cite

P. S. S. Soujanya, Sikander A. K. Lodhi (2018). Comparison of intravitreal triamcinolone and posterior subtenon triamcinolone in diffuse diabetic macular edema. Indian Journal of Clinical and Experimental Ophthalmology, 4(1), 50-55. https://europub.co.uk/articles/-A-474186