Comparison of Ketamine versus Fentanyl as an adjuvant with Propofol for inserting Laryngeal Mask Airway

Journal Title: Indian Journal of Clinical Anaesthesia - Year 2017, Vol 4, Issue 2

Abstract

Materials and Methods: 120 adult, ASA 1 and 2 patients were randomly allocated into two groups, propofol-ketamine (PK) and propofol-fentanyl (PF), (n=60 in each group) Baseline parameters- oxygen saturation (SpO2), Mean Blood Pressure (BP), Pulse Rate (PR) and End Tidal carbon dioxide (EtCO2), were recorded following which 1µg/ kg Fentanyl to the PF group & 0.5 mg/kg Ketamine to the PK group was given intravenously. Induction was initiated with infusion of 1% Propofol @ 1mg/ kg/ min with a syringe pump to avoid apnea. Tolerance to jaw thrust was regarded as end point for LMA insertion. Statistical analysis done by Parametric and non parametric values were analyzed using student’s unpaired t-test and Mann Whitney’s U test respectively. Intragroup differences analyzed by one-way ANOVA with significance using Tukey’s method. The incidence of apnea was analyzed using Chi- square test. P<0.05 was considered significant. Results: There was a significant(P<0.05) fall in heart rate, the systolic, diastolic & mean arterial pressures, from baseline to LMA insertion in the propofol-fentanyl group when compared to propofol-ketamine group. No significant difference in the insertion conditions was noted between the two groups. None of the patients in either of the two groups had any significant adverse events. Conclusion: we conclude that propofol-ketamine preserves hemodynamic and ventilatory stability compared to propofol-fentanyl, while providing similar LMA insertion conditions. Key Message: Infused Propofol - ketamine combination can be a better alternative to Infused propofol fentanyl for induction and insertion of LMA in selected group of patients where maintenance of blood pressure and ventilation are utmost important during induction.

Authors and Affiliations

Mohan Kumar RM, Muralidhara Danappa Patel, Hemavathi Balachander, Satyen Parida

Keywords

Related Articles

Pretreatment of magnesium sulphate accelerates neuromuscular block as compared to vecuronium priming – A randomized trial

Background: Action of non depolarising neuromuscular relaxants can be potentiated by small dose of priming. Priming reduces the time of onset of muscle relaxants by binding and occupying the choline receptors. Whereas ma...

A prospective, randomized, double blind, systemic controlled trial to compare analgesic efficacy of clonidine and fentanyl in supraclavicular block with 0.75% ropivacaine

Introduction and Object Fentanyl and clonidine mostly used as adjuvant to improve quality and duration of nerve block In present study we compared clonidine and fentanyl perineurally and systemically in Supraclavicular B...

Oral premedication in children: Comparison of combination of midazolam-ketamine and oral midazolam- A Randomised trial

Introduction Premedication with sedative drugs is often used in paediatric practice as one of the modalities to reduce preoperative anxiety in children undergoing surgery It reduces both patient and parental anxiety and...

Comparison of Ketamine versus Fentanyl as an adjuvant with Propofol for inserting Laryngeal Mask Airway

Materials and Methods: 120 adult, ASA 1 and 2 patients were randomly allocated into two groups, propofol-ketamine (PK) and propofol-fentanyl (PF), (n=60 in each group) Baseline parameters- oxygen saturation (SpO2), Mean...

Ease of ProSeal laryngeal mask airway insertion in children (after placement) using suction catheter: A comparison with conventional techniques

Objectives The ProSeal Laryngeal Mask Airway PLMA mostly inserted by finger technique and by an introducer tool method Recently a newer Suction Catheter Guided SC insertion technique has been successfully used in childre...

Download PDF file
  • EP ID EP312664
  • DOI 10.18231/2394-4994.2017.0044
  • Views 104
  • Downloads 0

How To Cite

Mohan Kumar RM, Muralidhara Danappa Patel, Hemavathi Balachander, Satyen Parida (2017). Comparison of Ketamine versus Fentanyl as an adjuvant with Propofol for inserting Laryngeal Mask Airway. Indian Journal of Clinical Anaesthesia, 4(2), 208-213. https://europub.co.uk/articles/-A-312664