Comparison of lipid profile and new atherogenic indices among the coronary artery disease (CAD)-negative and -positive diabetic dyslipidemia subjects
Journal Title: International Journal of Medical Science and Public Health - Year 2015, Vol 4, Issue 11
Abstract
Background: Type 2 diabetes mellitus (T2DM) is associated with a cluster of interrelated plasma lipid and lipoprotein abnormalities including reduced HDL cholesterol. Objective : To compare the lipid profile and new atherogenic indices among the coronary artery disease (CAD)-negative and -positive diabetic dyslipidemia subjects and determine the use of atherogenic indices in the early prediction of CAD in diabetic subjects. Materials and Methods: A total number of 194 subjects participated in our study, of which 65 people with diabetic dyslipidemia were considered cases and 129 nondiabetic people with normal lipid profile were considered control subjects based upon their fasting blood glucose (FBG) and lipid profiles. Furthermore, among the 65 cases, 38 subjects were identified as CAD negative and rest of the 27 subjects were CAD-positive subjects. Result: Lipid profiles of both CAD-negative and -positive diabetic subjects showed significantly different values than the control subjects except for high-density lipoprotein cholesterol (HDL-c) value (41.89 ± 1.49; p > 0.05) of CAD-negative subjects. The comparison between the CAD-negative and -positive diabetic dyslipidemia subjects observed signifi - cantly higher values of triglycerides (339.59 ± 52.24; p < 0.001) and very low-density lipoprotein cholesterol (VLDL-c) (67.91 ± 10.44; p < 0.001) and lower values of HDL-c (35.59 ± 1.40; p < 0.001) in CAD-positive subjects. When compared with control subjects, both CAD-negative and -positive subjects showed higher values of atherogenic indices that were significantly ( p < 0.01 and p < 0.001, respectively) different. Conclusion: Our results indicate that atherogenic indices may be useful for identifying individuals at higher risk of cardiovascular disease in the clinical practices, especially, not markedly deranged or in centers with insufficient resources.
Authors and Affiliations
Pusapati Madan Ranjit, Girija Sankar Guntuku, Ramesh Babu Pothineni
Keywords
Related Articles
- EP ID EP106525
- DOI 10.5455/ijmsph.2015.11052015326
- Views 104
- Downloads 0
A rare case of transverse vaginal septum
Transverse vaginal septum is a rare condition that results from incomplete fusion between the vaginal components of the mullerian ducts and the urogenital sinus. A patient presented with the complaint of aparunia. A pedi...
Study on stress among first-year medical students of Kurnool Medical College, Kurnool
Background: Stress is an inevitable part of medical education, and lack of adequate stress-coping skills may affect the students variedly. Objective: To study the magnitude and causes of stress among first-year m...
Cytology findings of the thyroid lesions with the histopathology findings correlation
Background: The gold standard in the detection of thyroid swellings is fine needle aspiration cytology (FNAC), particularly to eliminate the necessity of surgery. Objective: (1) To introduce FNAC as a routine dia...
Comparison of fine-needle aspiration technique with Ziehl–Neelsen stains in diagnosis of tuberculous lymphadenitis
Background: Lymphadenopathy is one of the most common clinical presentation among patients. In developing countries such as India, tuberculous (TB) lymphadenitis is one of the common causes of lymphadenopathy. Cytomorp...
A cross - sectional study on knowledge and attitude regarding kangaroo mother care practice among health care providers in Ahmedabad District
Background: One of the main reasons that Low Birth Weight (LBW) babies are at greater risk of illness and death is that they lack ability to control their body temperature. Kangaroo Mother Care (KMC) is a powerful...