Comparison of Lurasidone and Olanzapine in Schizophrenia- A Open label study
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 3
Abstract
The study was conducted at RIMS general Hospital Psychiatry OP and study evaluated comparative efficacy and safety Lurasidone in comparison to Olanzapine in first episode schizophrenia diagnosed based on ICD-10.126 first episode schizophrenia patients participated in the study out which 60 patients were in olanzapine group and 66 patients Lurasidone group. PANSS and CGI-I were used assess and compare efficacy. Lurasidone was non inferior to olanzapine in decreasing PANSS score from baseline to end of study at 12th week (95% CI: -8.9 to 4.5). Lurasidone and Olanzapine were equally effective in treating the first episode schizophrenia. Conclusion: In our study after analysis Lurasidone was equally efficacious in treating first episode of schizophrenia.
Authors and Affiliations
Dr A. Vijaya Chandra Reddy
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