Comparison of midazolam versus clonazepam as premedication scheduled for elective abdominal hysterectomies

Journal Title: International Journal of Medical Research and Review - Year 2016, Vol 4, Issue 8

Abstract

Background and aim: Anxiety is one of the most common problem which affect the patient during surgical procedures. Thus, anxiolytics have a primary role as premedication preoperatively. With this background, we designed this study to compare anxiolytic effects of oral midazolam and oral clonazepam. Methods: Study was carried out in 80 patients scheduled for elective Abdominal hysterectomy and were divided into group of 40 each. Group M 40 patients were given Tab Midazolam 10 mg, 45 min before surgery. Group C of 40 patients were given Tab Clonazepam 2 mg, 45 min before surgery with a sip of water. All hemodynamic parameters, sedation score, satisfactory score, Hamitlon Anxiety Rating Scale were noted. The patient characteristics were analysed using “Chi-square test” and inter group comparison of the parametric data was done using the “unpaired t-test using software IBM SPSS 17.0. Results: Clonazepam is better anxiolytic than midazolam and has longer duration of anxiolytic effects and with minimal side effects and better hemodynamic stability than midazolam. Conclusion: Tab Clonazepam can be used as premedication to allay anxiety in the patients undergoing elective surgeries

Authors and Affiliations

Neeru Bala, Hardip Singh, Joginder Pal Attri, Lipsy Bansal, Sukhman Kaur

Keywords

Related Articles

Oral manifestations of type 2 diabetes mellitus of Bhopal city: an observational prospective study

Introduction: Type 2 diabetes mellitus involves a variety of dysfunctions bringing about a few delicate tissue variations from the norm in the oral cavity. These incorporate gingivitis periodontitis, salivary dysfunction...

Hypoplasia of lung a rare entity mimicking as a case of tuberculosis

Pulmonary hypoplasia, a congenital malformation, is characterized by incomplete development of the lungs, leading to an abnormally less number or dimensions of bronchopulmonary segments / alveoli resulting in small fibro...

Resuscitation of trauma patients- an overview

Trauma is a major cause of mortality worldwide. Majority of trauma deaths occurs within 24 hours of injury. Survival depends on timely resuscitation. Initial evaluation uses primary survey involving Airway maintenance, B...

Prevalence of exposure to passive smoking and awareness about its ill effects among medical college undergraduate students in Mangalore

Introduction: Passive smoking, it is the combination of side stream smoke given off by a burning tobacco product and mainstream smoke exhaled by a smoker. Exposure to passive smoking can take place in the home, the workp...

Vitamin D and Diabetic Retinopathy in Indian adults with Type 2 Diabetes Mellitus

Objective: To find an association with Vitamin D levels and Diabetic retinopathy (DR). Methods: In a prospective clinical study, 412 Type 2 DM patients were evaluated for their ophthalmic findings. All patients underwent...

Download PDF file
  • EP ID EP231135
  • DOI 10.17511
  • Views 143
  • Downloads 0

How To Cite

Neeru Bala, Hardip Singh, Joginder Pal Attri, Lipsy Bansal, Sukhman Kaur (2016). Comparison of midazolam versus clonazepam as premedication scheduled for elective abdominal hysterectomies. International Journal of Medical Research and Review, 4(8), 1330-1334. https://europub.co.uk/articles/-A-231135