Comparison of Optic Nerve Head and Retinal Nerve Fibre Layer Thickness Analysis by Spectral Domain OCT
Journal Title: Ophthalmology and Allied Sciences - Year 2017, Vol 3, Issue 2
Abstract
Purpose: The aim of the study was to compare optic nerve head (ONH) and Retinal nerve fibre layer (RNFL) thickness tomographic parameters measured by Spectral Domain (SD) OCT and to identify which measurements are best able to differentiate between normal and glaucomatous eyes in Indian population. Design: Cross sectional prospective diagnostic study. Methods: Participants were recruited from a universitybased clinic. 30 age matched normal and 30 Open angle glaucomatous eyes who full filled the inclusion criteria were selected. All cases were subjected for optic nerve head (ONH) and Retinal nerve fibre layer (RNFL) thickness evaluation with the SD OCT (Carl Zeiss). All parameters were compared with normal eyes. The areas under the receiver operating curves AROC were calculated for each single parameter and then compared. Results: Comparative analysis of SDOCT parameters revealed statistically significant difference in all five RNFL parameters between both the groups. Most of the ONH parameters demonstrated statistically significant difference in glaucoma group when compared with control group. The inferior quadrant (0.976) and average RNFL thickness (0.970) obtained the highest AROC values in open angle glaucoma group. The rim area had the best diagnostic accuracy among the ONH parameters (AROC = 0.951). Conclusion: In the present study, RNFL parameters presented with better discriminatory abilities than ONH parameters in the normal and glaucomatous group. Out of all the RNFL and ONH parameters inferior quadrant RNFL thickness, average RNFL thickness and rim area had the best ability to discriminate between glaucomatous and normal eyes.
Authors and Affiliations
Sumita Karandikar
Keywords
Related Articles
- EP ID EP470505
- DOI 10.21088/oas.2454.7816.3217.1
- Views 113
- Downloads 0
Occurrence of Glaucoma among Fishermen Community of Naliya Taluka of Kutch District: An Observational Study
Aim: To determine the Occurrence of glaucoma and risk factors for primary openangle glaucoma among fishermen community of Naliya taluka of Kutch district. Material and Methods: A Observational Study was conducted to asse...
Clinical Study of Thyroid Orbitopathy
Aim: To study the age, sex, causal distribution, incidence and various modes of presentation of Thyroid Orbitopathy. Methods: 40 patients with a diagnosis of Thyroid Orbitopathy seen between October 2016 - October 2018 w...
Penetrating Keratoplasty : A Boon in Different Corneal Diseases to Improve Social Life
Introduction: Corneal Opacity is common cause of ocular morbidity. Occurrence of Corneal blindness alters from nation to nation and from population to population. There is even variation within the developing countries l...
Prevalence of Ocular Morbidity among School Children
Introduction: No one can deny the fact that the eyes are the most important of our sense organs. Good eyesight plays a vital constructive role in the development of the faculties of the child. Most of our knowledge and s...
Management of Cataract with Different Approach
Background and Objectives: Cataract surgery is the major cause of blindness in the world. For developing countries MSICShas come in as savior simple and effective. Surgical techniques are continually modified and improve...