Comparison of Oral Misoprostol and Oxytocin for Labour Induction in Prelabour Rupture of Membranes at Term
Journal Title: Indian Journal of Obstetrics and Gynecology - Year 2018, Vol 6, Issue 4
Abstract
Introduction: Prelabour rupture of membrane complicates pregnancy affecting delivery route and course of labour. This study aims at comparison of oral misoprostol and oxytocin infusion for labour induction in term PROM. Objective: To compare efficacy and safety of oral misoprostol with oxytocin infusion for induction of labour in term PROM. Methods: The study is retrospective study carried on 100 pregnant women admitted in department of OBGY, ACPM medical College, Dhule from June 2015-June 2017. The women were assigned randomly to anyone of 2 equal groups. Group A received 25 micrograms of misoprostol every 4 hrs for maximum of 4 doses. Group B received oxytocin infusion primigravida 2 IU diluted in IV fluid and multigravida with 2.5 IU diluted in IV fluid with maximum dose of 5 IU in primigravida and 2.5 IU in multigravida. The primary outcome was induction delivery interval. The secondary outcomes were mode of delivery, maternal and neonatal outcomes. Results: The study showed that mean induction delivery interval was significantly lower (5.6hrs) in misoprostol group as compared to oxytocin group (7.2hrs). In misoprostol administered group 78% patients delivered by vaginal route while in oxytocin group it was 70% whereas 22% required Caesarean Section in misoprostol group while it was 30% in oxytocin group. Incidence of hypertonus was higher (22%) in misoprostol group as compared to oxytocin group (10%). Conclusion: In our study, the time intervals from induction to delivery were significantly shorter in misoprostol group than oxytocin group. Meconium stained liquor was seen more in women induced with misoprostol group than oxytocin. Intravenous oxytocin is still an effective option.
Authors and Affiliations
Alka Patil
Keywords
Related Articles
- EP ID EP549900
- DOI 10.21088/ijog.2321.1636.6418.1
- Views 50
- Downloads 0
Role of Uterine Artery Doppler in Second Trimester in Predicting Adverse Pregnancy Outcome
Aim of the Study: The uterine artery Doppler has potentials for screening for complications of impaired placentation like preeclampsia and adverse fetaloutcomes.The purpose of this study was to determine the role of uter...
Case Series on Peripartum Cardiomyopathy
Introduction: Peripartum cardiomyopathy is an idiopathic and reversible form of dilated cardiomyopathy. It is defined as systolic heart failure in the last month of pregnancy or within 5 months of delivery. With an unkno...
A Clinicopathological Study of Endometriosis with Special Reference to Endometriosis in Very Rare Locations
Endometriosis is a chronic debilitating disease that occurs in 6-10% of the female population and about 35-50% of women with pain, infertility or both and characterized by endometrial tissue outside the uterine cavity. E...
Hypertensive Disorders in Pregnancy: Role of Platelet Indices
Introduction: The present study aimed to assess whether changes in platelet indices, during pregnancy could be used as markers for prediction of development of hypertensive disorders of pregnancy. Methods: A total of 255...
Acute Uterine Inversion with 2nd Degree Perineal Tear
Introduction: The acute peurperal uterine inversion is a rare obstetric emergency and a severe complication occurring in the third stage of labour. The diagnosis of uterine inversion is made on the basis of clinical symp...