Comparison of Perioperative Anaesthesia using Epidural Ropivacaine, Ropivacaine with Clonidine and Ropivacaine with Dexmeditomedine in Abdominal Hysterectomies
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 4
Abstract
Background: General Anesthesia or Regional anesthesia (Spinal/Epidural) is the technique used for Abdominal Hysterectomy surgeries. Regional anesthesia is preferred for lower abdominal surgeries. Local anaesthetics used commonly are Lignocaine, Bupivacaine & Ropivacaine. Clonidine and Dexmeditomedine are α2-adrenoreceptor agonists with anxiolytic and dose-related sedative properties. In addition to above properties, they provide good analgesia devoid of respiratory depression and good adjuncts to local anaesthetics. Aim 1. To compare the clinical effects of epidural Dexmedetomidine and epidural Clonidine when used as adjuvant to epidural Ropivacaine 2. To find out the time of first epidural top up. 3. To find the number of analgesic requirement until the time of first epidural top up. Materials And Methods This study was conducted after obtaining approval of institutional technical committee and Human Ethical committee of Government Medical College Trivandrum. Study design: Prospective cohort study Study setting: Government Medical College Trivandrum. 120 patients were selected and divided into 3 groups randomly. First group received Ropivacaine alone(R), second Ropivacaine plus Clonidine(RC) and third group Ropivacaine plus Dexmeditomedine(R). Inclusion Criteria Patients undergoing elective Abdominal Hysterectomy (ASA) I & II Age 30 – 60 years Weight 40 – 80 kg Height 145 – 165 cm Exclusion Criteria Patient refusal Patients on sympathomimetics, sympatholytic or anticholinergic drugs Known hypersensitivity to Dexmedetomidine/clonidine/local anaesthetics
Authors and Affiliations
Dr Chitra V. R
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