Comparison of Physiological Changes between Transperitoneal and Retroperitoneal Approach for Urologic Laparoscopic Surgery

Journal Title: Journal of Clinical and Diagnostic Research - Year 2018, Vol 12, Issue 4

Abstract

ABSTRACT Introduction: Laparoscopy is increasingly being performed for urologic surgeries either through transperitoneal or retroperitoneal approach. While physiological changes during transperitoneal surgeries have been extensively studied, very few studies have explored the effect of retroperitoneal laparoscopy. Aim: To compare physiological changes that occurred when urologic laparoscopic surgeries were carried out through either transperitoneal or retroperitoneal approach in lateral positions. Primary outcome was respiratory changes and haemodynamic changes were considered secondary outcome. Materials and Methods: This single centre prospective non randomised human study was conducted in 46 healthy individuals undergoing elective urologic laparoscopic surgeries at Dr. H.L. Trivedi Institute of Transplantation Sciences, Ahmedabad, Gujarat, India, from January 2017 to July 2017 and patients were divided into two groups according to the surgical approach used: 1) Transperitoneal (Trans) group; and 2) Retroperitoneal (Retro) group. Compliance, Peak Inspiratory Pressure (PIP), Minute Ventilation (MV), Heart Rate (HR) and Mean Arterial Pressure (MAP) were monitored at defined time interval. Arterial blood gases were also measured to compare Partial Pressure of Arterial Oxygen/Fraction of Inspired Oxygen (PaO2/FiO2) ratio. Chi-square and t-test were used for statistical comparison between the two groups. A p-value<0.05 was considered significant. Results: PaO2/FiO2 ratio improved in Trans (from 395.45±128.35 to 439.88±87.77) and decreased in Retro group (from 399.29±57.6 to 349.72±97.89) at the end of pneumoperitoneum with significant statistical difference between the two groups. Compliance decreased to 37% of baseline (from 33.03 to 20.99 mL/cm H2O in Trans group and from 37.02 to 23.23 mL/cm H2O in Retro group) and PIP increased to 45% from baseline (from 18.43 to 26.13 cm H2O in Trans group and from 17.91 to 25.86 cm H2O in Retro group) in both the groups without any statistical difference. The HR remained higher in Trans group as compared to Retro group during the insufflation period. The MAP remained higher than baseline during pneumoperitoneum in both the groups. Statistical comparison of HR and MAP between the two groups was insignificant. Conclusion: Respiratory and haemodynamic parameters remain stable and are comparable between the two approaches. Larger studies are required to validate this results.

Authors and Affiliations

Rajkiran Shah, Rajnish Nama, Beena Butala, Geeta Parikh, Shivani Pancholi, Raghunandana Gowda

Keywords

Related Articles

Serum Urokinase Plasminogen Activator as a Novel Biological Marker for COPD- A Review

ABSTRACT Chronic Obstructive Pulmonary Disease (COPD), a progressive disease of the airways is associated with chronic inflammation of respiratory passages that leads to irreversible lung dysfunction and distinct morphol...

CA-19-9 as an Emerging Marker of Ovarian Tumour: A Rare Entity

ABSTRACT Tumour markers are widely used in clinical practice for diagnosis; follow-up, prognosis and to predict recurrence of certain malignancies. Markers for ovarian cancer include CA-125 antigen, CA-15-3 antigen, and...

An Uncommon Presentation of Brucella Endocarditis Masquerading as Neurobrucellosis

Brucella endocarditis is a rare but a severe complication of brucellosis, observed in less than 2% of cases. It is the main cause responsible for up to 80% of deaths in brucellosis. Herein, we present a case of brucella...

Adenocarcinoma of the Sigmoid Colon Following Ureterosigmoidostomy: A Rare Long Term Sequela

ABSTRACT Carcinoma developing at the Ureterosigmoidostomy (US) anastomosis is a complication known to us. Patients generally present late because of non specific symptoms like loin pain, loss of appetite and weight loss....

Download PDF file
  • EP ID EP523950
  • DOI 10.7860/JCDR/2018/34030.11394
  • Views 72
  • Downloads 0

How To Cite

Rajkiran Shah, Rajnish Nama, Beena Butala, Geeta Parikh, Shivani Pancholi, Raghunandana Gowda (2018). Comparison of Physiological Changes between Transperitoneal and Retroperitoneal Approach for Urologic Laparoscopic Surgery. Journal of Clinical and Diagnostic Research, 12(4), 4-7. https://europub.co.uk/articles/-A-523950