Comparison of serum CRP levels in healthy controls and different stages of COPD
Journal Title: International Journal of Medical Science and Public Health - Year 2015, Vol 4, Issue 11
Abstract
Background : Chronic obstructive pulmonary disease (COPD) is the leading cause of morbidity and mortality in developing and developed countries. Objective : To compare the serum C-reactive protein (CRP) levels in healthy controls and patients with COPD. Materials and Methods : Serum CRP levels were evaluated in 100 healthy controls and 100 patients with COPD. Serum CRP levels were estimated and Pulmonary function tests were done in controls and patients with COPD. Results were drawn and analyzed using appropriate statistical tests. Result : In this study, values of CRP in patients with COPD and healthy control subjects were estimated and compared. When these values of mean serum CRP levels in control subjects were compared with those of total patients with COPD using unpaired t -test, it showed statistically highly significant difference with P < 0.001. A highly significant difference between mean CRP levels in stages III and IV was observed. Highly significant difference between mean CRP levels in healthy controls and patients of all stages with COPD individually was observed. Correlation test was applied, and Pearson’s correlation coefficient was calculated between serum CRP levels and predicted FEV 1 % (forced expiratory volume in 1 s expressed as percentage) showing a negative correlation with a value of - 0.564 (between 0 and - 1). Conclusion: There was a significant difference in the mean serum CRP levels between patients with COPD and healthy control subjects, as the mean serum CRP level was higher in patients with COPD and the difference was statistically highly significant. There was increase in CRP level with the increase in severity of the disease in different stages ( P < 0.001). There was a significant difference between the severity of dyspnea (FEV 1 % predicted) and the level of CRP ( P = 0.001).
Authors and Affiliations
Chinchole S Baburao, Najan A Bhausaheb, Sudhir Chaudhary
Keywords
Related Articles
- EP ID EP153812
- DOI 10.5455/ijmsph.2015.28042015314
- Views 80
- Downloads 0
A comparative study of ultrasonographic birth weight with neonatal birth weight in a first referral unit of Guwahati
Background: Examining fetal growth regularly is a regular component of antenatal care. Several equations have been formulated by investigators for calculating fetal weight in the late second and the third trimeste...
Effect of training among health care workers on change in knowledge regarding biomedical waste management according to new rules of 2016
Background: Adequate knowledge about the health hazards of hospital waste, proper techniques and methods of handling the waste, and practice of safety measures can improve the safe disposal of hazardous hospital waste an...
Utilization of library services by medical students: A comparative analysis of undergraduate and postgraduate students in a medical college
Background: The rapid proliferation of information in the present era has important implications for the education and library usage of health professionals including medical students. Objectives: (1) To determine the ex...
Premenstrual syndrome knowledge and attitude among women attending family medicine clinics, King Khalid Military Hospital, Tabuk city
Background: Various studies in India have observed an incidence of premenstrual syndrome (PMS) to be 20% in general population, with 8% revealing severe symptoms. Objective: To study the sociodemographic characteristic...
A study on dietary intake among school going adolescent girls in rural and urban area of Jamnagar District, Gujarat
Background: During adolescent period, rapid changes in physical growth and psychosocial development have placed these young adults in nutritionally vulnerable groups with poor eating habits that fail to meet essential di...