COMPARISON OF SIDE EFFECTS OF MISOPROSTOL BY ORAL AND RECTAL ROUTES IN ACTIVE MANAGEMENT OF THIRD STAGE OF LABOUR
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 3
Abstract
BACKGROUND Every year, there are 14 million cases of PPH. It accounts for about 25% of maternal deaths worldwide. This can be reduced by active management of third stage of labour. Administration of misoprostol after delivery of neonate has been shown to be effective in reducing amount of blood loss during delivery. The aim of the study is to compare the side effects of misoprostol in terms of distribution, frequency and severity by oral and rectal route for active management of third stage of labour. MATERIALS AND METHODS A prospective randomised study conducted on 100 women in labour in Department of OBG in MVJMC and RH. They were divided into 2 groups of 50 parturient mothers each group receiving misoprostol (600 µg) by oral route (Group 1) and rectal route (Group 2). Outcome of these women were noted in terms of blood loss, duration of 3rd stage of labour and side effects like shivering, fever, diarrhoea, nausea and vomiting. RESULTS There was not much difference in amount of blood loss and duration of third stage among the two groups. However, side effects were more in the group receiving misoprostol orally (32%) as compared to that receiving by rectal route (14%). CONCLUSION In the present study, both oral and rectal routes are effective in active management of third stage of labour. However, rectal route has lesser side effects.
Authors and Affiliations
Ratna Bulusu, Payel Ray, Anupama Rani, Payal Handa
Keywords
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- EP ID EP212939
- DOI 10.18410/jebmh/2017/29
- Views 72
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