[Comparison of Th1 and Th2 response in the blood of tuberculous patients and healthy contacts].
Journal Title: Advances in Respiratory Medicine - Year 2009, Vol 77, Issue 5
Abstract
Th1 response is known to play a dominant role in the resistance to tuberculosis. Nevertheless, IFN gamma levels are frequently increased in tuberculous patients, especially at the site of the disease. It is also possible that the shift toward Th2 response is responsible for the loss of resistance. The aim of this study was to compare the Th1 function of peripheral blood cells and the levels of antimycobacterial antibodies in the serum of culture positive tuberculosis patients and healthy tuberculosis (Tb) contacts. The correlation between the levels of antimycobacterial antibodies and Th1 function of blood cells was also evaluated.
Authors and Affiliations
Jolanta Winek, Urszula Demkow, Ewa Rowińska-Zakrzewska, Małgorzata Szołkowska, Jacek Jagodziński, Kazimierz Roszkowski-Sliz
Keywords
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