Comparison of the analytical techniques of hba1c estimation by immunoturbidimetric and HPLC methods in diabetic and pre- diabetics patients

Journal Title: International Journal of Clinical Biochemistry and Research - Year 2017, Vol 4, Issue 2

Abstract

Aims & Objectives: The aim of the study is to compare the available analytical methods of measurement of HbA1c like immunoturbidimetric and HPLC methods. Materials and Method: Total of 150 pre-diabetic and diabetic patients are included in the study. HbA1c was measured by immunoturbidimetric and HPLC methods as these are the common methods used by the clinical laboratories. Results: The HbA1c values of two methods have a significant difference. The value of immunoturbidimetric method was less than the HPLC method. The two methods correlated with the correlation coefficient of 0.972. Conclusion: Both the methods are reliable and show a strong correlation .Even though the immunoturtbidimetric values are low it is specific and more cost effective than the HPLC methods. HPLC is a sensitive method.

Authors and Affiliations

A . G. Thivyah Prabha

Keywords

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  • EP ID EP296934
  • DOI 10.18231/2394-6377.2017.0043
  • Views 51
  • Downloads 0

How To Cite

A . G. Thivyah Prabha (2017). Comparison of the analytical techniques of hba1c estimation by immunoturbidimetric and HPLC methods in diabetic and pre- diabetics patients. International Journal of Clinical Biochemistry and Research, 4(2), 187-190. https://europub.co.uk/articles/-A-296934