Comparison of the Effects of Artemisia Vaginal Cream and Clotrimazole on Vaginal Candidiasis Infection
Journal Title: Acta Facultatis Medicae Naissensis - Year 2018, Vol 34, Issue 4
Abstract
Candida vaginitis is the second most common vaginal infection which is treatable by azole. Over-consumption of azole is associated with resistance to drug and treatment failure. Studies conducted in laboratory conditions confirm the anti-fungal effects of Artemisia plant. The aim of this study was to compare the effect of vaginal Artemisia cream and clotrimazole on vaginal candidiasis infection. This is a clinical triple-blind trial that was performed on 72 non-pregnant women referred to Mashhad health centers in 2012-2017. After confirmation of Candida infection, the research units were randomly allocated into two groups: Artemisia and clotrimazole vaginal cream recipients treated for 7 nights. After the treatment, the data were analyzed by SPSS software (version 24). The results of the study showed that the mean reduction in the score of signs and symptoms of vaginal Candida infection was 7.4 ± 4. 1 and 7.6 ± 3.8 in the Artemisia and clotrimazole group, respectively. Wilcoxon test showed that improvement in both groups treated by Artemisia and clotrimazole was significantly higher than before treatment (p < 0.001). There was no significant difference between the two groups regarding the impro-vement of symptoms (p > 0.05). The present study showed that Artemisia vaginal cream and clotrimazole cream both improved the symptoms related to vaginal Candida infection. In addition, the therapeutic effect of the two drugs was not statistically significant in comparison with each other. Therefore, it can be used as an alternative treatment for vaginal candidiasis.
Authors and Affiliations
Ala Saber Mohammad, Samira Ebrahimzadeh Zagami, Nahid Golmakani, Mohammad Javad Asili, Ali Naseri, Mahmood Parian-Novghani, Azaddeh Saki
Keywords
Related Articles
- EP ID EP422403
- DOI 10.2478/afmnai-2018-0032
- Views 106
- Downloads 0
QSAR MODELOVANJE DERIVATA KUMARINA KAO POTENTNIH INHIBITORA HIV-1 INTEGRAZE BAZIRANO NA MONTE KARLO METODI I STUDIJE MOLEKULARNOG DOKINGA ODABRANIH 4-FENIL HIDROKSIKUMARINA
U potrazi za novim i obećavajućim kumarinskim jedinjenjima koja su inhibitori HIV-1 integraze veoma značajnu ulogu imaju hemoinformatičke metode, kao što je modelovanje kvantitativnog odnosa strukture i aktivnosti (QSAR)...
EVALUATION OF SOME ANATOMICAL AND ANTHROPOMETRIC CHARACTERISTICS OF THE CHEST BASED ON THE ANALYSIS OF DIGITAL IMAGES OF THE ANTERIOR ASPECT OF TRUNK IN TOP ATHLETES
The aim of this research was to assess the size and shape of the chest in students and top athletes. The research involved 23 first-year students of the Faculty of Sport and Physical Education, and 23 top athletes of the...
ODREĐIVANJE SADRŽAJA KLINDAMICIN FOSFATA U RAZLIČITIM FORMULACIJAMA VAGINALNIH GELOVA METODOM REVERZNO-FAZNE VISOKOEFIKASNE TEČNE HROMATOGRAFIJE
Klindamicin je antibiotik efikasan protiv Gram-pozitivnih aeroba, kao i Gram-pozitivnih i Gram-nega-tivnih anaerobnih patogena. Klindamicin (njegov fosfatni estar) korišćen je u ovoj studiji u cilju procene efikasnosti f...
DOSTIZANJE CILJNIH VREDNOSTI KRVNOG PRITISKA KOD BOLESNIKA SA PRELEŽANIM INFARKTOM MIOKARDA I ŠEĆERNOM BOLEŠĆU
Iako je arterijska hipertenzija važan faktor koji doprinosi kardiovaskularnim komplikacijama kod koronarnih bolesnika sa i bez dijabetesa mellitusa (DM), dostizanje ciljnih vrednosti krvnog pritiska se u praksi retko ost...
Surgical Treatment of an Open Elbow Dislocation with Vascular Injury: A Case Report - - - Hirurško lečenje otvorene luksacije lakta sa povredom magistralnih krvnih sudova: prikaz slučaja
Open elbow dislocations with vascular injury are rare injuries and they most commonly occur after a fall from a high or in sports accidents. Close anatomic proximity of the joint to the neurovascular structures put them...