Comparison of three different concentrations of epidural ropivacaine (0.05%, 0.1% & 0.2%) for labor analgesia: A prospective randomized and double blind study

Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 3

Abstract

Introduction Epidural infusionof02ropivacaine is recommended by the manufacturer forlaboranalgesia but lower concentrations may be effective The present work is a clinical comparative study of different doses of ropivacaine ie 005 01 and 02 each with 2 mcgmL of fentanyl to find out minimum effective concentration of ropivacaine that can be used safely in epidural labor analgesiaMaterials and Methods The study was conducted on sixty 60 parturient of ASA grade I and grade II physical status in labor with single fetus vertex position between 3742 weeks gestation with regular contractions true labor pain with 46 cm cervix dilatation and who had requested labor analgesia Parturients were then allocated randomly to one of three groups with 20 parturients in each group Group 1 received 005 ropivacaine with 2 mcgmL fentanyl Group 2 received 01 ropivacaine with 2 mcgmL fentanyl and Group 3 received 02 ropivacaine with 2 mcgmL fentanyl After completion of the study the nonparametric data of the study was analyzed with Kruskal Wallis test and parametric data of the study was analyzed with ANOVA test and p value of 0Results Patient demographics and labor characteristics were comparable in all the groups Ropivacaine 005 with 2 mcgmL of fentanyl produced adequate analgesia for labor and delivery in only 50 of parturient while ropivacaine 01 ropivacaine 02 with 2 mcgmL of fentanyl produced adequate analgesia in 90 of parturient in group II and group III Reduction in local anesthetic was not associated with any change in incidence of motor block or instrumental deliveriesConclusion We concluded that the minimum concentration which can be used safely for labor analgesia with no adverse effect is 01 of ropivacaine with 2 mcgmL fentanyl Keywords Epidural Labor analgesia Ropivacaine Fentanyl

Authors and Affiliations

Kunal Singh, Hariom Khandelwal, Shikha Agarwal, Ashutosh Singh, Prithwis Bhattacharya

Keywords

Related Articles

Comparative study between thoracic epidural and general anesthesia for modified radical mastectomy

Objective: Comparison between thoracic epidural and general anesthesia for breast surgeries. Aim: The aim was to compare general anesthesia and thoracic epidural anesthesia in patients undergoing breast cancer surgeries...

A comparison of oral clonidine versus oral midazolam as premedication in adults

Introduction: Premedication is an important aspect in anaesthesia. We conducted a double blind randomised controlled study to compare the clinical efficacy of oral premedication using clonidine 200 µg versus midazolam 15...

Anesthetic considerations in an infant with congenital cystic adenomatoid malformation

Congenital cystic adenomatoid malformation (CCAM) is a rare developmental disorder of lower respiratory tract in which child presents with severe respiratory distress, pneumonitis or sepsis. Anesthetic management of such...

Efficacy of intrathecal α2 agonists as adjuvants with low dose of levobupivacaine for lower limb surgeries in elderly patients

Introduction: Elderly orthopedic patients are frequently associated with systemic co morbidities like cardiac, pulmonary or endocrinal disorders. Regional anaesthesia has benefits over general anaesthesia in elderly. But...

Ease of ProSeal laryngeal mask airway insertion in children (after placement) using suction catheter: A comparison with conventional techniques

Objectives The ProSeal Laryngeal Mask Airway PLMA mostly inserted by finger technique and by an introducer tool method Recently a newer Suction Catheter Guided SC insertion technique has been successfully used in childre...

Download PDF file
  • EP ID EP476506
  • DOI 10.18231/2394-4994.2018.0076
  • Views 79
  • Downloads 0

How To Cite

Kunal Singh, Hariom Khandelwal, Shikha Agarwal, Ashutosh Singh, Prithwis Bhattacharya (2018). Comparison of three different concentrations of epidural ropivacaine (0.05%, 0.1% & 0.2%) for labor analgesia: A prospective randomized and double blind study. Indian Journal of Clinical Anaesthesia, 5(3), 403-406. https://europub.co.uk/articles/-A-476506