Comparison of three different concentrations of epidural ropivacaine (0.05%, 0.1% & 0.2%) for labor analgesia: A prospective randomized and double blind study
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 3
Abstract
Introduction Epidural infusionof02ropivacaine is recommended by the manufacturer forlaboranalgesia but lower concentrations may be effective The present work is a clinical comparative study of different doses of ropivacaine ie 005 01 and 02 each with 2 mcgmL of fentanyl to find out minimum effective concentration of ropivacaine that can be used safely in epidural labor analgesiaMaterials and Methods The study was conducted on sixty 60 parturient of ASA grade I and grade II physical status in labor with single fetus vertex position between 3742 weeks gestation with regular contractions true labor pain with 46 cm cervix dilatation and who had requested labor analgesia Parturients were then allocated randomly to one of three groups with 20 parturients in each group Group 1 received 005 ropivacaine with 2 mcgmL fentanyl Group 2 received 01 ropivacaine with 2 mcgmL fentanyl and Group 3 received 02 ropivacaine with 2 mcgmL fentanyl After completion of the study the nonparametric data of the study was analyzed with Kruskal Wallis test and parametric data of the study was analyzed with ANOVA test and p value of 0Results Patient demographics and labor characteristics were comparable in all the groups Ropivacaine 005 with 2 mcgmL of fentanyl produced adequate analgesia for labor and delivery in only 50 of parturient while ropivacaine 01 ropivacaine 02 with 2 mcgmL of fentanyl produced adequate analgesia in 90 of parturient in group II and group III Reduction in local anesthetic was not associated with any change in incidence of motor block or instrumental deliveriesConclusion We concluded that the minimum concentration which can be used safely for labor analgesia with no adverse effect is 01 of ropivacaine with 2 mcgmL fentanyl Keywords Epidural Labor analgesia Ropivacaine Fentanyl
Authors and Affiliations
Kunal Singh, Hariom Khandelwal, Shikha Agarwal, Ashutosh Singh, Prithwis Bhattacharya
Keywords
Related Articles
- EP ID EP476506
- DOI 10.18231/2394-4994.2018.0076
- Views 84
- Downloads 0
A randomized clinical comparative trial to study the efficacy of adding Clonidine or Dexamethasone to Bupivacaine(0.5%) in prolonging the duration of post operative analgesia with ultrasound guided TAP block in cesarean delivery
Introduction: With dramatic rise in the rate of cesarean deliveries in the last two decades, post-operative pain management of these patients has become a major medical challenge. We studied the efficacy of adding dexame...
Evaluation and comparison of intravenous clonidine and intravenous dexmedetomidine on duration of bupivacaine spinal anesthesia
Context: Alpha-2 agonists improve the block characteristics in regional anesthesia, when added to local anesthetics. Aim: To evaluate and compare efficacy of dexmedetomidine and clonidine, as an intravenous adjuvant to i...
Anaesthetic management of an Extremely Low Birth Weight (ELBW) neonate with multiple co-morbidities
Anaesthetic management of an extremely low birth weight (ELBW) neonate is always a challenge. Challenges are substantial beginning from pre-operative preparation till the neonate has been shifted to the neonatal intensiv...
Study of addition of fentanyl to bupivacaine in subarachnoid block administered for cemented bipolar prosthesis in geriatric patients population
Introduction The most restricting component of regional anaesthesia in geriatric patients is hypotension inspite of several advantages The present study aimed to reduce hypotensive effect of local anaesthetics by reducin...
Effect of propofol & sevoflurane on jugular bulb oxygen saturation in patients undergoing brain tumor surgery
Introduction: Sevoflurane, and Propofol are widely used for anesthesia during intracranial surgery. All these drugs reduce the cerebral metabolic rate (CMR) for oxygen (CMRO2). In contrast to their similar effect on cere...