Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy
Journal Title: International Journal of Medical Reviews and Case Reports - Year 2018, Vol 2, Issue 4
Abstract
Leprosy is chronic infectious disease caused by the intracellular parasitic pathogen Mycobacterium Leprae involves accumulation of highly reactive oxygen species (ROS) production and decreased levels of antioxidant in affected individuals. The present treatment method available for leprosy is MDT (Multi Drug Therapy) from WHO (World Health Organization) involves combination of Rifampicin, Dapsone and Clofazimine. In this cohort prospective study, we have investigated total antioxidant capacity (TAC) in 16 multibacillary leprosy patients before and after 3 months of MDT-MB WHO. In this study, we present that mean values of total antioxidant capacity (TAC) after 3 months of MDT-MB WHO were higher than before treated. From the sample groups in this study, we also found an decrease TAC levels in higher bacterial index after 3 months of MDT-MB WHO, this further increases significantly (p<0.05). Hence we conclude that 3 months giving of MDT-MB WHO increase the total antioxidant capacity.
Authors and Affiliations
Dinie Ramdhani Kusuma, Safruddin Amin, Khairuddin Djawad, Srivitayani Muchtar, Sitti Nur Rahmah, Idham Jaya Ganda, Agussalim Bukhari
Keywords
Related Articles
- EP ID EP534594
- DOI 10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-typ
- Views 108
- Downloads 0
EFFECT OF CURCUMA LONGA 0.5% EXTRACT ON SEBUM COMPOSITION AND SKIN MOISTURE IN DRY SKIN PATIENTS
Introduction Dry skin is a problem for millions of people and often causes discomfort and even psychological stress. Curcuma Longa (C. Longa) has been known to have an effect in improving skin texture due to exogenous ef...
Case report of Dengue encephalopathy in pregnancy mimicking atypical eclampsia – An insight of neurological manifestations of dengue in pregnancy
Dengue is a global public health problem. Dengue in pregnancy carries a high maternal and perinatal morbidity and even mortality especially when the diagnosis is delayed. Often dengue with hemorrhagic shock syndrome is m...
Efficacy of Intravenous immunoglobulin and phototherapy in the management of extreme-hyperbilirubinaemia: A Case Report
A case report of a term male neonate with extreme-hyperbilirubinaemia secondary to ABO incompatibility who was effectively managed with a combination of guided phototherapy and Intravenous immunoglobulin (IVIG) was prese...
Vulvar non-filarial elephantiasis associated with scabies
Vulvar elephantiasis is a very rare condition often caused by filariasis infection. Other causes like general inflammatory disease, cancer treatment, traumatic causes or other infections can also explain the occurrence o...
An uncommon complication of a common procedure: aberrant placement of a catheter into the ureter following suprapubic cystostomy
A 70-year-old man was admitted with fever and urinary retention. Suprapubic catheter (SPC) was placed following failed attempts to catheterise due to a urethral stricture. The patient subsequently improved and a micturat...