Comparison of Ultrasonographic Findings with Histo Pathological Findings of Thyroid Nodules - A Two Year Study
Journal Title: International Journal of Contemporary Medicine surgery and Radiology - Year 2018, Vol 3, Issue 3
Abstract
Introduction: Thyroid USG plays an important role in demonstrating thyroid anatomy and pathological conditions with remarkable clarity. The frequency of thyroid nodules by sonographic evaluation is 13% to 67% based on various literature reports globally. The present study was aimed to evaluate Ultrasonographic morphological features predictive of both benign and malignant thyroid nodules and correlation with FNAC. Material and methods: A two year prospective study was conducted among patients with thyroid nodules. Ultrasonogram was performed with detailed clinical examination and history taking along with colour Doppler study and differentiated into benign and malignant. FNAC was performed on cases with suspicious malignancy and nodular goitre. Diagnostic statistics viz. Sensitivity, Specificity, PPV, NPV and Accuracy have been computed to find the correlation of Ultrasound and Histopathological diagnosis. P value: 0.05<P<0.10 was considered significant. Results: 50 cases with 82% females were included. Majority (54%) of cases were of solitary nodules and of 50 cases based on USG, 74% were Benign and 26% malignant but by FNAC, 78% were benign and 22% were malignant. Vascularity, margins, calcification, cystic degeneration and halo were found with significant association with malignancy. (P value<0.01) Sensitivity and specificity of USG for differentiating benign and malignant thyroid nodules were 90.91% and 92.86%. Discussion: Our study strongly recommends that features of USG of thyroid nodules are highly suggestive in determining the nodules as benign or malignant and clearly guides in performing FNAC. Our study suggests that Elastography and Colour Doppler USG are newer techniques which are introduced and may be good tools in determining the cases of malignant thyroid nodules. However the techniques are to be standardized.
Authors and Affiliations
Srinivas Metta, Aditya Nutakki
Keywords
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- EP ID EP424240
- DOI 10.21276/ijcmsr.2018.3.3.7
- Views 113
- Downloads 0
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