Comparison of Vitamin D Levels in Allergic Patients with and Without Asthma
Journal Title: Bagcilar Medical Bulletin - Year 2019, Vol 4, Issue 4
Abstract
Objective: To determine whether serum vitamin D levels had a relationship with pulmonary function test (PFT) results and serum immunoglobulin E (IgE) levels in allergic patients with and without asthma. Method: The study group was comprised of patients who had positive allergy skin tests with and without asthma (n=31, n=28, respectively) and healthy controls (n=31). The skin allergy test (prick test) and PFT were performed on all of the study groups. Also, the patients’ serum vitamin D and IgE levels were determined. Comparisons among these groups and also subgroups of the patients were investigated in addition to correlation analyses for vitamin D, IgE and PFT results. Results: Seventy percent of the asthma group was found to have abnormal PFT results, while all healthy controls and non-asthmatic patients had normal PFT results (p<0.001). IgE levels were significantly higher in asthma and non-asthma groups compared to the control group (p=0.024). Asthma and non-asthma groups were similar regarding the frequency of multiple allergic factors (p=1.000). In terms of vitamin D levels, the asthma group and the non-asthma group were similar, while the healthy control group was found to have a significantly higher mean vitamin D level than both groups. Conclusion: The results of our study indicate that vitamin D levels are lowered in patients with allergies; however, no association with asthma was determined. Additionally, we found no correlations between vitamin D, IgE and PFT results. The literature on this topic is highly conflicted and there is a requirement for future studies that evaluate vitamin D levels according to covariates.
Authors and Affiliations
Ayşe Sezim Şafak, Fuat Bulut
Keywords
Related Articles
- EP ID EP684255
- DOI 10.4274/BMB.galenos.2019.11.025
- Views 164
- Downloads 0
Comparative Evaluation of the First-grade and Senior Medical School Students’ Knowledge and Attitudes Toward Thoracic Surgery
Objective: Comparison of the knowledge and attitudes of first and last year medical students about thoracic surgery. Method: The answers of the five questionnaires which were directed to the first and last year medicine...
A Neglected Giant Cervical Intradural Extramedullary Tumor
Primary spinal tumors are rarely seen, and representing 4-8% of all central nervous system tumors. Extradural tumors constitute approximately 40% of intraspinal tumors whereas intradural-extramedullary tumors make up the...
Local Effects of Papaverine on Normal, Atherosclerotic, and Vasospastic Carotid Arteries of Rabbits: An Experimental Study
Objective: Papaverine is a direct-acting vasodilating agent that is frequently used in the treatment of vasospasm after subarachnoid hemorrhage. However, not much knowledge is available about the effect of papaverine on...
Expanding Intensive Care Unit Management for Critically Ill Patients During COVID-19 Pandemic
No Abstract
The Brain Ischemic Volume Correlation with the Ischemic Modified Albumin Level
Objective: Cerebrovascular disease is a frequent cause of emergency department visits, and early diagnosis can reduce mortality and morbidity. It was aimed to evaluate the relationship between diffusion-weighted-magnetic...