Comparison of white blood cells parameters in patients with acute schizophrenia, unipolar depression and bipolar disorder
Journal Title: Archives of Psychiatry and Psychotherapy - Year 2017, Vol 19, Issue 3
Abstract
Aim of the study We compared white blood cells parameters (total white blood cells (WBC), lymphocytes count (LYMPH#) and percentage (LYMPH%), monocytes count (MONO) and percentage (MONO%), basophils count (BASO#) and percentage (BASO%), eosinophils count (EO#) and percentage (EO%), neutrophils count (NEUT#) and percentage (NEUT%)) in patients with schizophrenia (SHZ), unipolar depression (UD) and bipolar disorder (BIP): bipolar depression (BD) and mania (BM). Subject or material and methods This was a retrospective, cross-sectional, naturalistic study of 2381 patients (SHZ n=1244; UD n=794; BIP n=343, BD n=259, BM n=84). WBC as well as differential leukocytes count were measured using automated hematology analyzer. Results There were significant differences between study groups (WBC, p=0.02; LYMPH# p=0.03; LYMPH% p=0.008; EO% p <0.001). Age and sex affected various white blood cells parameters. Discussion Highest WBC was in the schizophrenia and bipolar mania groups, while patients with BM had lowest LYMPH%. Highest frequency of below or above normal WBC was found in patients with BM. Conclusions There are differences in white blood cells between study groups.
Authors and Affiliations
Adam Wysokiński, Aleksandra Margulska
Keywords
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