Comparitive Analysis of Broder & Bryne’s Grading of Squamous Cell Carcinoma in Different Anatomical Sites
Journal Title: IOSR Journal of Research & Method in Education (IOSRJRME) - Year 2018, Vol 8, Issue 2
Abstract
Squamous cell carcinoma (SCC) is an epithelial malignancy that occurs in organs that are normally covered with squamous epithelium. Development of early diagnostic and cost effective methods can reduce mortality. Bryne developed a simple morphological malignancy grading system that restricts the evaluation to the deep invasive front of the tumour. The present study was conducted in the Department of Pathology at Subharti Medical College and associated ChhatrapatiShivaji Hospital, Meerut, from June 2014– May 2017. Total 173 cases were collected. All the lesions were categorised according to anatomical sites. Maximum cases of moderately differentiated squamous cell carcinoma were in oral cavity (32.4%) and upper aerodigestive tract (23.1%). Tumours were classified according to Broder’s and Bryne’s classification. 12 cases graded as moderately differentiated by Broder’s system were categorized as low-grade malignancy grade (grade I of Bryne’s) in our study considering the histological invasive parts of tumour and other parameters. This new malignancy grading system can change the course of treatment of cancer patients and might give a better outcome. It would be more economical and will save time.
Authors and Affiliations
Ankurgoyal . , Vinay Bharat, Mamta .
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