Complete Pathological Response in a Young Patient with Poorly Differentiated Gastric Adenocarcinoma Following Flot Neoadjuvant Chemotherapy: A Case Report
Journal Title: International Journal of Health & Medical Research - Year 2024, Vol 3, Issue 08
Abstract
Gastric cancer remains a significant health issue, particularly when occurring in younger populations with more aggressive forms and poorer outcomes. Here, we present the case of a 24-year-old female diagnosed with poorly differentiated gastric adenocarcinoma. She presented with severe epigastric pain, progressive dysphagia, hyper salivation, melena, and significant weight loss. Diagnostic evaluations revealed a subcardial mass suggestive of Bormann type III gastric cancer. Following a multidisciplinary decision, neoadjuvant chemotherapy with the FLOT regimen was initiated, resulting in a 10% reduction in tumor size. The patient underwent spleen-preserving total gastrectomy with Roux-en-Y reconstruction and extensive lymph node dissection. Postoperative pathology showed no residual neoplasm or lymph node metastasis. This case highlights the importance of a multimodal approach, demonstrating the efficacy of the FLOT regimen in achieving a complete pathological response and underscores the potential for favorable outcomes even in rare and aggressive cases of gastric cancer.
Authors and Affiliations
Hajri Amal, Jamaleddine Khalid, El Kabbaj Abderrahmane, Elwassi Anas, Erguibi Driss, Boufettal Rachid, Rifki Jai Saad, Chehab Farid,
Keywords
Related Articles
- EP ID EP750576
- DOI 10.58806/ijhmr.2024.v3i08n07
- Views 54
- Downloads 0
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