Complex disposition of an enigmatic pathogen: rare electron microscopic manifestations in nasal rhinosporidiosis
Journal Title: Romanian Journal of Rhinology - Year 2017, Vol 7, Issue 27
Abstract
Rhinosporidiosis is a polypoidal disease of the nose and mucocutaneous tissues, the diagnosis of which is based on the presence of round bodies believed to be causative agents of the disease. Historically, the round body has been considered to be a sporangium of a fungus Rhinosporidium seeberi but without any convincing evidence. Round bodies contain numerous daughter cells, which are likely in the infective stage and are shed through a rupture in the wall of the round body. The released single-celled organisms eventually develop into round bodies on availability of suitable transformative trigger and favourable environment. Surgical excision of the polyp by electrocautery is the only effective treatment; however, recurrence may occur due to spillage of infective endospores in the surrounding mucosa during removal. There are many enigmatic features of the causative agent of this disease, which have been baffling researchers for more than a century. Here we present some rare electron microscopic and previously unreported features of the coat of the round body and single-celled organism in nasal rhinosporidiosis.
Authors and Affiliations
Dhara B. Dhaulakhandi, Alok K. Ravi, Lalit C. Garg, Karvita B. Ahluwalia
Preliminary outcomes in transcutaneous neuromuscular electrical stimulation use in patients with dysphagia
Dysphagia is a common disorder associated with a large number of etiologies like aging, stroke, traumatic brain injury, head and neck cancer, neurodegenerative disorders, structural changes or congenital abnormalities. T...
Endoscopic and histological staging: Deciding factors in the treatment of chronic rhinosinusitis
Chronic rhinosinusitis represents an infl ammatory condition of the nose and paranasal sinuses, characterized by two or more symptoms. The diagnosis of acute rhinosinusitis is made, most often, clinically; however, in th...
Invasive fungal rhinosinusitis
Invasive fungal rhinosinusitides are a group of disorders with three subtypes (acute invasive fungal rhinosinusitis, chronic invasive fungal rhinosinusitis and granulomatous invasive fungal rhinosinusitis), requiring urg...
Olfactometric assessment - where do we stand today?
Having an enormous importance not only in one’s quality of life, but also in one’s health and personal safety, the olfactory function assessment has begun to gain more and more interest amongst the ENT practitioners. How...
The effect of smartphone usage on the upper extremity performance among Saudi Youth, KSA
The current study aims to investigate the effect of smartphone usage on the upper extremity performance among Saudi youth. A goniometer to measure the Range of Motion (ROM), the Smartphone Addiction Scale (SAS), McGill P...